Adenocarcinoma in situ of the lung
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Adenocarcinoma in situ (AIS) of lung refers to a relatively new entity for a pre invasive lesion in the lung. This entity partly replaces the non invasive end of the previous term bronchoalveolar carcinoma. AIS is defined as a localized adenocarcinoma of less than 3 cm, that exhibits a lepidic pattern with neoplastic cells along the alveolar structures but without stromal, vascular, or pleural invasion 1.
Radiographic features
HRCT chest
While AIS is usually seen a pure ground glass nodule or a part-solid lung nodule, there can be is an overlap among the imaging features of AAH, AIS, and invasive adenocarcinoma of lung 1.
PrognosisTreatment and prognosis
AIS carries an excellent prognosis with reported survival rates following complete resection at 100%.
See also
-<p><strong>Adenocarcinoma in situ (AIS) of lung</strong> refers to a relatively new entity for a pre invasive lesion in the lung. This entity partly replaces the non invasive end of the previous term <a href="/articles/adenocarcinoma-in-situ-and-minimally-invasive-adenocarcinoma-in-lung" title="Bronchoalveolar carcinoma">bronchoalveolar carcinoma</a>. AIS is defined as a localized adenocarcinoma of less than 3 cm, that exhibits a lepidic pattern with neoplastic cells along the alveolar structures but without stromal, vascular, or pleural invasion <sup>1</sup>.</p><h4>Radiographic features</h4><h5>HRCT chest</h5><p>While AIS is usually seen a pure <a href="/articles/ground-glass-density-nodule" title="Ground glass nodule">ground glass nodule</a> or a <a href="/articles/part-solid-lung-nodule" title="part-solid lung nodule">part-solid lung nodule, </a>there can be is an overlap among the imaging features of AAH, AIS, and invasive adenocarcinoma of lung <sup>1</sup>.</p><h4>Prognosis</h4><p>AIS carries an excellent prognosis with reported survival rates following complete resection at 100%.</p><h4>See also</h4><ul>-<li><a href="/articles/non-small-cell-lung-cancer" title="NSCLC">non small cell lung cancer</a></li>-<li><a href="/articles/atypical-adenomatous-hyperplasia-of-the-lung" title="Atypical adenomatous hyperplasia (AAH) of the lung">atypical adenomatous hyperplasia (AAH) of lung</a></li>-<li><a href="/articles/minimally-invasive-adenocarcinoma-mia-of-lung" title="minimally invasive adenocarcinoma (MIA) of lung">minimally invasive adenocarcinoma (MIA) of lung</a></li>-</ul>- +<p><strong>Adenocarcinoma in situ (AIS) of lung</strong> refers to a relatively new entity for a pre invasive lesion in the lung. This entity partly replaces the non invasive end of the previous term <a href="/articles/adenocarcinoma-in-situ-and-minimally-invasive-adenocarcinoma-in-lung">bronchoalveolar carcinoma</a>. AIS is defined as a localized adenocarcinoma of less than 3 cm, that exhibits a lepidic pattern with neoplastic cells along the alveolar structures but without stromal, vascular, or pleural invasion <sup>1</sup>.</p><h4>Radiographic features</h4><h5>HRCT chest</h5><p>While AIS is usually seen a pure <a href="/articles/ground-glass-density-nodule">ground glass nodule</a> or a <a href="/articles/part-solid-lung-nodule">part-solid lung nodule, </a>there can be is an overlap among the imaging features of AAH, AIS, and invasive adenocarcinoma of lung <sup>1</sup>.</p><h4>Treatment and prognosis</h4><p>AIS carries an excellent prognosis with reported survival rates following complete resection at 100%.</p>
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