Adenoid cystic carcinoma of the salivary glands
Updates to Article Attributes
Adenoid cystic carcinoma (ACC) of the salivary glands is the second most common malignancy involving the minor salivary glands and behind mucoepidermoid carcinoma and the second most common malignancy involving the parotid gland.
Pathology
Adenoid cystic carcinomas arise more commonly in the minor salivary glands (~55%) than in the major salivary glands. They are the most common sinonasal tumours of salivary orignorigin. They are locally aggressive with a propensity for perineural spread 5.
Radiographic features
CT
Generally, a distinction is made radiologically between low-grade and high-grade adenoid cystic carcinomas. Low-grade tumours tend to be well-defined, in contradistinction to high-grade tumours, which appear infiltrative. However, both subtypes are usually homogeneously enhancing after contrast administration.
Adenoid cystic carcinomas are frequently associated with perineural spread (via cranial nerve VII), which is well appreciated on MRI.
MRI
Signal characteristics
- T1: hypo- to isointense
- T2: slightly hyperintense, with higher grades being markedly hyperintense
- T1 C+ (Gd): homogeneous enhancement
See also
-<p><strong>Adenoid cystic carcinoma (ACC)</strong> <strong>of the salivary glands</strong> is the most common malignancy involving the <a href="/articles/minor-salivary-glands">minor salivary glands</a> and the second most common malignancy involving the <a href="/articles/parotid-gland">parotid gland</a>.</p><h4>Pathology</h4><p>Adenoid cystic carcinomas arise more commonly in the minor salivary glands (~55%) than in the major salivary glands. They are the most common sinonasal tumours of salivary orign. They are locally aggressive with a propensity for perineural spread <sup>5</sup>. </p><h4>Radiographic features</h4><h5>CT</h5><p>Generally, a distinction is made radiologically between low-grade and high-grade adenoid cystic carcinomas. Low-grade tumours tend to be well-defined, in contradistinction to high-grade tumours, which appear infiltrative. However, both subtypes are usually homogeneously enhancing after contrast administration.</p><p>Adenoid cystic carcinomas are frequently associated with <a href="/articles/perineural-spread-of-tumour">perineural spread</a> (via <a href="/articles/cranial-nerve-vii">cranial nerve VII</a>), which is well appreciated on MRI.</p><h5>MRI</h5><h6>Signal characteristics</h6><ul>- +<p><strong>Adenoid cystic carcinoma (ACC)</strong> <strong>of the salivary glands</strong> is the second most common malignancy involving the <a href="/articles/minor-salivary-glands">minor salivary glands</a> behind mucoepidermoid carcinoma and the second most common malignancy involving the <a href="/articles/parotid-gland">parotid gland</a>.</p><h4>Pathology</h4><p>Adenoid cystic carcinomas arise more commonly in the minor salivary glands (~55%) than in the major salivary glands. They are the most common sinonasal tumours of salivary origin. They are locally aggressive with a propensity for perineural spread <sup>5</sup>. </p><h4>Radiographic features</h4><h5>CT</h5><p>Generally, a distinction is made radiologically between low-grade and high-grade adenoid cystic carcinomas. Low-grade tumours tend to be well-defined, in contradistinction to high-grade tumours, which appear infiltrative. However, both subtypes are usually homogeneously enhancing after contrast administration.</p><p>Adenoid cystic carcinomas are frequently associated with <a href="/articles/perineural-spread-of-tumour">perineural spread</a> (via <a href="/articles/cranial-nerve-vii">cranial nerve VII</a>), which is well appreciated on MRI.</p><h5>MRI</h5><h6>Signal characteristics</h6><ul>
References changed:
- 5. Yih W, Kratochvil F, Stewart J. Intraoral Minor Salivary Gland Neoplasms: Review of 213 Cases. J Oral Maxillofac Surg. 2005;63(6):805-810. <a href="https://doi.org/10.1016/j.joms.2005.02.021">doi:10.1016/j.joms.2005.02.021</a>
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