Ancient schwannoma

Changed by Frank Gaillard, 4 May 2017

Updates to Article Attributes

Body was changed:

Ancient schwannomas are long-standing, slow benign (WHO grade i) slow growing schwannomas with advanced degeneration. These can have calcification, hyalinization, and cystic cavitation that can be identified on imaging. The term “ancient” has been traditionally used to describe schwannomas showing degenerative changes and diffuse hypocellular areas1-3.

Although microscopically these tumours can have nuclear pleomorphism they should not be misinterpreted as being malignant 4

  • -<p><strong>Ancient schwannomas</strong> are long-standing, slow growing <a href="/articles/schwannoma">schwannomas</a> with advanced degeneration. These can have calcification, hyalinization, and cystic cavitation that can be identified on imaging. The term “ancient” has been traditionally used to describe schwannomas showing degenerative changes and diffuse hypocellular areas.</p>
  • +<p><strong>Ancient schwannomas</strong> are long-standing, benign (WHO grade i) slow growing <a href="/articles/schwannoma">schwannomas</a> with advanced degeneration. These can have calcification, hyalinization, and cystic cavitation that can be identified on imaging. The term “ancient” has been traditionally used to describe schwannomas showing degenerative changes and diffuse hypocellular areas <sup>1-3</sup>.</p><p>Although microscopically these tumours can have nuclear pleomorphism they should not be misinterpreted as being malignant <sup>4</sup>. </p>

References changed:

  • 4. Louis DN, Ohgaki H, Wiestler OD et-al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007;114 (2): 97-109. <a href="http://link.springer.com/article/10.1007/s00401-007-0243-4/fulltext.html">Acta Neuropathol. (full text)</a> - <a href="http://dx.doi.org/10.1007/s00401-007-0243-4">doi:10.1007/s00401-007-0243-4</a> - <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929165">Free text at pubmed</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/17618441">Pubmed citation</a><span class="ref_v3"></span>

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