Angiolipoma

Changed by Yaïr Glick, 21 May 2017

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Angiolipomas (also sometimes known as haemangiolipomas, vascular lipomas, and fibromyolipomas) are rare soft tissue tumours composed of mature adipocytes and vessels. They can occur essentially anywhere, and can be subclassified into infiltrating and non-infiltrating varietiesvariants 1

The most common locations are the extremities and the soft tissues of the neck and trunk 2.

Please refer to the epidural (spinal) angiolipoma article for a specific discussion. The remainder of this article describedescribes the general features of peripheral angiolipomas.

Epidemiology

Typically occur in young adults, appearing on the forearm (most common location), trunk and upper arm. They are more common in males. The most common presentation is of multiple, small (<2 cm), subcutaneous, tender nodules 2,3.

Infiltrating angiolipomas are much rarer than the non-infiltrating variant. They occur in children and adults and have no sex predilection. They most commonly appear in the muscles of the lower extremity, neck, and shoulder, and are usually painless 5.

Radiographic features

As expected, these masses contain a mixture of softadipose tissue and fatty components, with prominent vascular supply.

Infiltrating angiolipoma is nonencapsulated and can contain phleboliths, heterotopic bone, and calcium salts. There are authors who conclude that it should be classified as an "intramuscular haemangioma" 2,4.

Ultrasonography

Appear as well-circumscribed, homogeneous hyperechoic masses 5,6.

MRI

Angiolipomas demonstrate heterogeneous signal due to mixtureintensity characteristics of fattymature adipose tissue. Vascular elements are T1-hypointense and non-fatty components. Non-fatty componentsT2 hyperintense and enhance vividly following administration of contrast 23.

Angiography

Catheter angiography demonstrates prominent coarse neovascularity. During the capillary phase, contrast staining is typically seen 1.

Treatment and prognosis

Treatment is predominantly surgical, although infiltrating tumours are difficult to completely excise 1 and, as mentioned above, tend to recur locally.2

  • -<p><strong>Angiolipomas</strong> (also sometimes known as <strong>haemangiolipomas</strong>, <strong>vascular lipomas</strong>, and <strong>fibromyolipomas</strong>) are rare soft tissue tumours composed of mature adipocytes and vessels. They can occur essentially anywhere, and can be subclassified into infiltrating and non-infiltrating varieties <sup>1</sup>. </p><p>The most common locations are the extremities and the soft tissues of the neck and trunk <sup>2</sup>.</p><p>Please refer to the <a href="/articles/epidural-angiolipoma">epidural (spinal) angiolipoma</a> article for a specific discussion. The remainder of this article describe the general features of peripheral angiolipomas.</p><h4>Radiographic features</h4><p>As expected these masses contain a mixture of soft tissue and fatty components, with prominent vascular supply.</p><h5>MRI</h5><p>Angiolipomas demonstrate heterogeneous signal due to mixture of fatty and non-fatty components. Non-fatty components enhance vividly following administration of contrast <sup>2</sup>. </p><h5>Angiography</h5><p>Catheter angiography demonstrates prominent coarse neovascularity. During the capillary phase, contrast staining is typically seen <sup>1</sup>.</p><h4>Treatment and prognosis</h4><p>Treatment is predominantly surgical, although infiltrating tumours are difficult to completely excise <sup>1</sup>.</p>
  • +<p><strong>Angiolipomas</strong> (also sometimes known as <strong>haemangiolipomas</strong>, <strong>vascular lipomas</strong>, and <strong>fibromyolipomas</strong>) are rare soft tissue tumours composed of mature adipocytes and vessels. They can occur essentially anywhere and can be subclassified into infiltrating and non-infiltrating variants <sup>1</sup>. </p><p>Please refer to the <a href="/articles/epidural-angiolipoma">epidural (spinal) angiolipoma</a> article for a specific discussion. The remainder of this article describes the general features of peripheral angiolipomas.</p><h4>Epidemiology</h4><p>Typically occur in young adults, appearing on the forearm (most common location), trunk and upper arm. They are more common in males. The most common presentation is of multiple, small (&lt;2 cm), subcutaneous, tender nodules <sup>2,3</sup>.</p><p>Infiltrating angiolipomas are much rarer than the non-infiltrating variant. They occur in children and adults and have no sex predilection. They most commonly appear in the muscles of the lower extremity, neck, and shoulder, and are usually painless <sup>5</sup>.</p><h4>Radiographic features</h4><p>As expected, these masses contain adipose tissue with prominent vascular supply.</p><p>Infiltrating angiolipoma is nonencapsulated and can contain phleboliths, heterotopic bone, and calcium salts. There are authors who conclude that it should be classified as an "intramuscular haemangioma" <sup>2,4</sup>.</p><h5>Ultrasonography</h5><p>Appear as well-circumscribed, homogeneous hyperechoic masses <sup>5,6</sup>.</p><h5>MRI</h5><p>Angiolipomas demonstrate signal intensity characteristics of mature adipose tissue. Vascular elements are T1-hypointense and T2 hyperintense and enhance vividly following administration of contrast <sup>3</sup>.</p><h5>Angiography</h5><p>Catheter angiography demonstrates prominent coarse neovascularity. During the capillary phase, contrast staining is typically seen <sup>1</sup>.</p><h4>Treatment and prognosis</h4><p>Treatment is predominantly surgical, although infiltrating tumours are difficult to completely excise <sup>1</sup> and, as mentioned above, tend to recur locally. <sup>2</sup></p>

References changed:

  • 2. Kransdorf MJ, Moser RP, Meis JM, Meyer CA. Fat-containing soft-tissue masses of the extremities. Radiographics : a review publication of the Radiological Society of North America, Inc. 11 (1): 81-106. <a href="https://doi.org/10.1148/radiographics.11.1.1996399">doi:10.1148/radiographics.11.1.1996399</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/1996399">Pubmed</a> <span class="ref_v4"></span>
  • 3. Gupta P, Potti TA, Wuertzer SD, Lenchik L, Pacholke DA. Spectrum of Fat-containing Soft-Tissue Masses at MR Imaging: The Common, the Uncommon, the Characteristic, and the Sometimes Confusing. Radiographics : a review publication of the Radiological Society of North America, Inc. 36 (3): 753-66. <a href="https://doi.org/10.1148/rg.2016150133">doi:10.1148/rg.2016150133</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/27163592">Pubmed</a> <span class="ref_v4"></span>
  • 4. Pribyl C, Burke SW, Roberts JM, Mackenzie F, Johnston CE. Infiltrating angiolipoma or intramuscular hemangioma? A report of five cases. Journal of pediatric orthopedics. 6 (2): 172-6. <a href="https://www.ncbi.nlm.nih.gov/pubmed/3958171">Pubmed</a> <span class="ref_v4"></span>
  • 5. Mintz AD, Mengoni P. Angiolipoma of the breast: sonographic appearance of two cases. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 17 (1): 67-9. <a href="https://www.ncbi.nlm.nih.gov/pubmed/9440111">Pubmed</a> <span class="ref_v4"></span>
  • 6. Lee JY, Kim SM, Fessell DP, Jacobson JA. Sonography of benign palpable masses of the elbow. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 30 (8): 1113-9. <a href="https://www.ncbi.nlm.nih.gov/pubmed/21795487">Pubmed</a> <span class="ref_v4"></span>
  • 2. Leu NH, Chen CY, Shy CG et-al. MR imaging of an infiltrating spinal epidural angiolipoma. AJNR Am J Neuroradiol. 2003;24 (5): 1008-11. <a href="http://www.ajnr.org/content/24/5/1008.full">AJNR Am J Neuroradiol (full text)</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/12748114">Pubmed citation</a><span class="auto"></span>

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