Angiomyofibroblastoma-like tumor of scrotum
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Article Attributes
Angiomyofibroblastoma like tumour of scrotum is a rare well-defined slow growing mesenchymal extratesticular nonepididymal tumour which rarely seen in perineum and scrotum of older male patients. A similar tumour can occur in the vulval region in females.
Epidemiology
They are rare but typically occur in vulva of premenopausal women. In males, they are even rarer and seen in middle age to elderly patients between 45-75 years old. In the majority of cases it has an indolent and nonaggressive clinical course; however, in minority focal invasion and recurrence has been reported.
Pathology
macroscopic
macroscopic
Superficialsuperficial well circumscribed with gray-white to yellow-brown colour.
high vascularity and perivascular fibrinoid hyalinisation
tumour cells are spindle cells with minimal atypia and mitosis
small amount of fat in 25-56%
Immunohistopathology
Positive for vimentin and negative for S100,actin actin, and CD 34.
Radiographic features
Ultrasound
Heterogeneous echotexture and iso i=echoic to the surrounding tissue and subcutaneous fat.
CT scan
Well circumscribed homogeneous subcutaneous oval mass with possible several small internal hypodense foci.
MRI
-
T1WIT1: low due to high fibrous contents -
T2WIT2:intermediate heterogeneous signal
Intense post contrast enhancement due to high vascularity of the lesions.
Treatment
Treatment is wide surgical resection to reduce recurrence rate.
Differential diagnosis
IncludesIn the scrotum, the differential includes rare lesions such as:
- spindle lipoma of scrotum
- liposarcoma of scrotum
- solitary fibrous tumour of scrotum
- leiomyoma of scrotum
- aggressive angiomyxoma of scrotum
-<p><strong>Angiomyofibroblastoma like tumour of scrotum </strong>is a rare well-defined slow growing mesenchymal extratesticular nonepididymal tumour which rarely seen in perineum and scrotum of older male patients.</p><h4>Epidemiology </h4><p>They are rare but typically occur in vulva of premenopausal women. In males, they are even rarer and seen in middle age to elderly patients between 45-75 years old. In the majority of cases it has an indolent and nonaggressive clinical course; however, in minority focal invasion and recurrence has been reported. </p><h4>Pathology</h4><h6>macroscopic</h6><p>Superficial well circumscribed with gray-white to yellow-brown colour.</p><h6>microscopic</h6><ul>-<li>high vascularity and perivascular fibrinoid hyalinisation</li>-<li>tumour cells are spindle cells with minimal atypia and mitosis</li>-<li>small amount of fat in 25-56%</li>-</ul><h6>Immunohistopathology</h6><p>Positive for vimentin and negative for S100, <span style="line-height:13.8667px">actin, and CD 34.</span><span style="line-height:13.8667px"> </span></p><h4>Radiographic features</h4><h5>Ultrasound</h5><p>Heterogeneous echotexture and iso i=echoic to the surrounding tissue and subcutaneous fat. </p><h5>CT scan</h5><p>Well circumscribed homogeneous subcutaneous oval mass with possible several small internal hypodense foci.</p><h5>MRI</h5><ul>-<li>T1WI: low due to high fibrous contents</li>-<li>T2WI:intermediate heterogeneous signal</li>-</ul><p>Intense post contrast enhancement due to high vascularity of the lesions.</p><h4>Treatment</h4><p>Treatment is wide surgical resection to reduce recurrence rate. </p><h4>Differential diagnosis</h4><p>Includes rare lesions such as:</p><ul>-<li>spindle lipoma </li>-<li>liposarcoma </li>-<li>solitary fibrous tumour</li>-<li>leiomyoma </li>-<li>aggressive angiomyxoma</li>- +<p><strong>Angiomyofibroblastoma like tumour of scrotum </strong>is a rare well-defined slow growing mesenchymal extratesticular nonepididymal tumour which rarely seen in perineum and scrotum of older male patients. A similar tumour can occur in the vulval region in females.</p><h4>Epidemiology </h4><p>In males, they seen in middle age to elderly patients between 45-75 years old. In the majority of cases it has an indolent and nonaggressive clinical course; however, in minority focal invasion and recurrence has been reported. </p><h4>Pathology</h4><ul>
- +<li>
- +<p><strong>macroscopic</strong></p>
- +<ul><li><p>superficial well circumscribed with gray-white to yellow-brown colour.</p></li></ul>
- +</li>
- +<li>
- +<strong>microscopic</strong><ul>
- +<li><p>high vascularity and perivascular fibrinoid hyalinisation</p></li>
- +<li><p>tumour cells are spindle cells with minimal atypia and mitosis</p></li>
- +<li><p>small amount of fat in 25-56%</p></li>
- +</ul>
- +</li>
- +</ul><h6>Immunohistopathology</h6><p>Positive for vimentin and negative for S100, actin, and CD 34. </p><h4>Radiographic features</h4><h5>Ultrasound</h5><p>Heterogeneous echotexture and iso i=echoic to the surrounding tissue and subcutaneous fat. </p><h5>CT scan</h5><p>Well circumscribed homogeneous subcutaneous oval mass with possible several small internal hypodense foci.</p><h5>MRI</h5><ul>
- +<li>
- +<strong>T1</strong>: low due to high fibrous contents</li>
- +<li>
- +<strong>T2</strong>:intermediate heterogeneous signal</li>
- +</ul><p>Intense post contrast enhancement due to high vascularity of the lesions.</p><h4>Treatment</h4><p>Treatment is wide surgical resection to reduce recurrence rate. </p><h4>Differential diagnosis</h4><p>In the scrotum, the differential includes rare lesions such as:</p><ul>
- +<li>spindle lipoma of scrotum</li>
- +<li>liposarcoma of scrotum</li>
- +<li>solitary fibrous tumour of scrotum</li>
- +<li>leiomyoma of scrotum </li>
- +<li>aggressive angiomyxoma of scrotum</li>
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