Aseptic loosening of hip joint replacements
Updates to Article Attributes
Body
was changed:
Aseptic loosening is considered relatively common complication of hip joint replacements. It is usually considered a long term-term complication and is often considered as the most common complication 3.
Pathology
The initial response to particulate debris includes a subtle inflammatory response, which becomes more pronounced as osteolysis progresses. This inflammatory environment provokes a cellular response which is characterizedcharacterised by elevated levels of secreted factors such as TNF, RANKL, IL-6, IL-1, and IL-11.
Radiographic features
Plain filmradiograph
A peri-implant lucency of greater than 2 mm or progressive change is considered a concerning feature. Stress views may show an interval change in position. The loosening is not lined by sclerosis. The features may include:
- medial migration of cement and cup mass
- change in inclination of the cup
-<p><strong>Aseptic loosening</strong> is considered relatively common <a href="/articles/complications-of-hip-joint-replacements">complication of hip joint replacements</a>. It is usually considered a long term complication and is often considered as the most common complication <sup>3</sup>.</p><h4>Pathology</h4><p>The initial response to particulate debris includes a subtle inflammatory response, which becomes more pronounced as osteolysis progresses. This inflammatory environment provokes a cellular response which is characterized by elevated levels of secreted factors such as TNF, RANKL, IL-6, IL-1, and IL-11.</p><h4>Radiographic features</h4><h5>Plain film</h5><p>A peri-implant lucency of greater than 2 mm or progressive change is considered a concerning feature. Stress views may show an interval change in position. The loosening is not lined by sclerosis. The features may include</p><ul>- +<p><strong>Aseptic loosening</strong> is considered relatively common <a href="/articles/complications-of-hip-joint-replacements">complication of hip joint replacements</a>. It is usually considered a long-term complication and is often considered as the most common complication <sup>3</sup>.</p><h4>Pathology</h4><p>The initial response to particulate debris includes a subtle inflammatory response, which becomes more pronounced as osteolysis progresses. This inflammatory environment provokes a cellular response which is characterised by elevated levels of secreted factors such as TNF, RANKL, IL-6, IL-1, and IL-11.</p><h4>Radiographic features</h4><h5>Plain radiograph</h5><p>A peri-implant lucency of greater than 2 mm or progressive change is considered a concerning feature. Stress views may show an interval change in position. The loosening is not lined by sclerosis. The features may include:</p><ul>
-<li>change in inclination of cup</li>- +<li>change in inclination of the cup</li>
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