Astrocytic tumors
Updates to Article Attributes
Astrocytic tumours are primary central nervous system (CNS) tumours. They arisetumours that either arises from astrocytes andor appear similar to astrocytes on histology having arisen from precursor cells. They are the most common tumours arising from glial tumourcells.
They can be divided into those that are diffuse in growth (the vast majority with poorer prognosis and given a, generally having higher grade (see diffuse astrocytoma gradingwhich tend(tend to have a lower grade and better prognosis).
- diffuse
-
Low-gradediffuse astrocytoma: WHO grade II(10-15% of astrocytomas) - anaplastic astrocytoma: WHO grade III (25% of astrocytomas)
- glioblastoma: WHO grade IV (50-60% of astrocytomas)
-
giant cell glioblastoma: WHO grade IV (rare) -
gliosarcoma: WHO grade IV (rare
-
- localised
- pilocytic astrocytoma: WHO grade I
-
pilomyxoid astrocytoma: WHO grade II - subependymal giant cell astrocytoma: WHO grade I
- pilomyxoid astrocytoma: ~WHO grade II
- pleomorphic xanthoastrocytoma: WHO grade II
Additionally, some tumours also containscontain astrocytic components, and it is often this component that dictated biological behaviour. Examples include:
All these tumours have strikingly differing imaging appearances, treatment and prognosis and thus they are, along with spinal astrocytomas discussed separately.
NB: gliomatosis cerebri, fibrillary astrocytoma and protoplasmic astrocytoma are no longer recognised in the current WHO classification of CNS tumours
-<p><strong>Astrocytic tumours</strong> are <a href="/articles/primary-cns-tumours">primary central nervous system (CNS) tumours</a>. They arise from astrocytes and are the most common <a href="/articles/glial-tumour">glial tumour</a>.</p><p>They can be divided into those that are diffuse in growth (the vast majority with poorer prognosis and given a higher grade (see <a href="/articles/diffuse-astrocytoma-grading">diffuse astrocytoma grading</a>) and those that are localised which tend to have a lower grade. </p><ul>- +<p><strong>Astrocytic tumours</strong> are primary central nervous system tumours that either arises from astrocytes or appear similar to astrocytes on histology having arisen from precursor cells. They are the most common tumours arising from <a title="Glial cells" href="/articles/glial-cells">glial cells</a>.</p><p>They can be divided into those that are diffuse in growth (the vast majority, generally having higher grade and poorer prognosis) and those that are localised (tend to have a lower grade and better prognosis). </p><ul>
-<a href="/articles/low-grade-astrocytoma">Low-grade astrocytoma</a>: <a href="/articles/who-classification-of-cns-tumours-1">WHO grade II</a> (10-15% of astrocytomas)<ul><li><a href="/articles/gemistocytic-astrocytoma">gemistocytic astrocytoma</a></li></ul>-</li>- +<a href="/articles/low-grade-astrocytoma">diffuse astrocytoma</a>: WHO grade II (10-15% of astrocytomas)</li>
-<li>-<a href="/articles/giant-cell-glioblastoma">giant cell glioblastoma</a>: WHO grade IV (rare)</li>-<li>-<a href="/articles/gliosarcoma">gliosarcoma</a>: WHO grade IV (rare<span style="display:none"> </span>-</li>-<a href="/articles/pilomyxoid-astrocytoma">pilomyxoid astrocytoma</a>: WHO grade II</li>-<li>- +<a href="/articles/pilomyxoid-astrocytoma">pilomyxoid astrocytoma</a>: ~WHO grade II </li>
- +<li>
-</ul><p>Additionally, some tumours also contains astrocytic components, and it is often this component that dictated biological behaviour. Examples include:</p><ul>- +</ul><p>Additionally, some tumours also contain astrocytic components, and it is often this component that dictated biological behaviour. Examples include:</p><ul>
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