Biotin

Changed by Rohit Sharma, 5 Apr 2024
Disclosures - updated 18 Aug 2023: Nothing to disclose

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Biotin (less, less commonly known as vitamin B7), and previously known as vitamin H or coenzyme R, is a water-soluble vitamin, part of the vitamin B complex, and a coenzyme for many reactions, including gluconeogenesis and the synthesis of fatty acids and amino acids.

Biotin deficiency is very rare.

Biotin excess does not seem to produce any ill-effects 3. However large doses of biotin in those on vitamin supplements may interfere with biochemical assays leading to misdiagnoses e.g. hyperthyroidism 4.

Recent work suggests that biotin may have a role in the treatment of secondary progressive multiple sclerosis5.

Interestingly, it was formerly known as vitamin H or coenzyme R.

  • -<p><strong>Biotin</strong> (less commonly known as <strong>vitamin B<sub>7</sub></strong>) is a water-soluble <a href="/articles/vitamins">vitamin</a>, part of the <a href="/articles/vitamin-b-complex">vitamin B complex</a>, and a coenzyme for many reactions, including gluconeogenesis and the synthesis of fatty acids and <a href="/articles/amino-acids-1">amino acids</a>.</p><p><a href="/articles/biotin-deficiency">Biotin deficiency</a> is very rare.</p><p>Biotin excess does not seem to produce any ill-effects <sup>3</sup>. However large doses of biotin in those on vitamin supplements may interfere with biochemical assays leading to misdiagnoses e.g. <a href="/articles/hyperthyroidism">hyperthyroidism</a> <sup>4</sup>.</p><p>Recent work suggests that biotin may have a role in the treatment of <a href="/articles/multiple-sclerosis">secondary progressive multiple sclerosis</a> <sup>5</sup>.</p><p>Interestingly, it was formerly known as vitamin H or coenzyme R.</p><p><!--EndFragment--></p>
  • +<p><strong>Biotin</strong>, less commonly known as <strong>vitamin B<sub>7</sub></strong>, and previously known as <strong>vitamin H</strong> or <strong>coenzyme R</strong>, is a water-soluble <a href="/articles/vitamins">vitamin</a>, part of the <a href="/articles/vitamin-b-complex">vitamin B complex</a>, and a coenzyme for many reactions, including gluconeogenesis and the synthesis of fatty acids and <a href="/articles/amino-acids-1">amino acids</a>.</p><p><a href="/articles/biotin-deficiency">Biotin deficiency</a> is very rare.</p><p>Biotin excess does not seem to produce any ill-effects <sup>3</sup>. However large doses of biotin in those on vitamin supplements may interfere with biochemical assays leading to misdiagnoses e.g. <a href="/articles/hyperthyroidism">hyperthyroidism</a> <sup>4</sup>.</p><p></p>

References changed:

  • 5. Mock DM. Biotin: From Nutrition to Therapeutics. (2017) The Journal of nutrition. 147 (8): 1487-1492. <a href="https://doi.org/10.3945/jn.116.238956">doi:10.3945/jn.116.238956</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/28701385">Pubmed</a> <span class="ref_v4"></span>

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