Bone mineral density

Changed by Craig Hacking, 15 May 2020

Updates to Article Attributes

Body was changed:

Bone mineral density (BMD) is defined as the amount of mineral (calcium hydroxyapatite) per unit of bone.

Radiographic features

BMD can be measured by various methods with DEXA the most prevalent:

  • gamma rays(gamma decay): replaced by radiographic methods
    • single-energy photon absorptiometry (SPA) was superseded by the introduction of single x-ray absorptiometry; both methods measure density at peripheral sites in the skeleton (e.g. distal radius, calcaneus), but the disadvantage is that it cannot measure trabecular and cortical bone separately
    • dual-energy photon absorptiometry (DPA) also has been replaced by dual-energy x-ray absorptiometry (DEXA)
  • x-ray
  • ultrasound
    • calcaneal ultrasonography: determines bone mineral density and bone strength
    • speed sound (SOS): measures velocity in the bone
    • broadband ultrasound attenuation (BUA): measures the frequency in the bone
  • CT
    • advantageous for opportunistic screening but research not advanced for implementation into clinical practice 4
    • HU measurements vary on anatomic site including by individual vertebra 4
    • scanner variability is also a significant factor with HU threshold for diagnosis of osteoporosis varying between 99 and 136 HU 4
  • MRI
    • spectroscopy
    • quantitative magnetic resonance imaging: depicts changes in the trabecular structures at several sites of the peripheral skeleton
  • -<p><strong>Bone mineral density (BMD)</strong> is defined as the amount of mineral (calcium hydroxyapatite) per unit of bone.</p><h4>Radiographic features</h4><p>BMD can be measured by various methods with DEXA the most prevalent</p><ul>
  • +<p><strong>Bone mineral density (BMD)</strong> is defined as the amount of mineral (calcium hydroxyapatite) per unit of bone.</p><h4>Radiographic features</h4><p>BMD can be measured by various methods with DEXA the most prevalent:</p><ul>
  • -<strong>gamma rays</strong>: replaced by radiographic methods<ul>
  • +<strong>gamma rays </strong>(<a title="Gamma decay" href="/articles/gamma-decay">gamma decay</a>): replaced by radiographic methods<ul>
  • -<li><a href="/articles/quantitative-computed-tomography">quantitative computed tomography (QCT)</a></li>
  • +<li><a href="/articles/quantitative-computed-tomography-bone-1">quantitative computed tomography (QCT)</a></li>

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.