Question 507
{"accessible":false,"alternatives":[{"id":2541,"text":"cerebral metastases"},{"id":2542,"text":"cerebral toxoplasmosis"},{"id":2543,"text":"multifocal glioblastoma"},{"id":2544,"text":"multiple sclerosis"},{"id":2545,"text":"primary CNS lymphoma"}],"archived":false,"correctAlternativeId":2543,"explanation":"\u003cp\u003eThe corpus callosum is an unusual location for metastases\u0026nbsp;and favors glioblastoma (multifocal in this case as there are multiple areas of enhancement) or CNS lymphoma. Central non-enhancement is unusual in lymphoma unless treated or immunocompromised. Multiple sclerosis is uncommon in a previously well 60-year-old and usually has open-ring enhancement. Similarly, toxoplasmosis is usually seen in the setting of an\u0026nbsp;immunocompromised state.\u0026nbsp;\u003c/p\u003e","id":507,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/2330","nextQuestionPath":"/articles/brain-metastases/questions/466","relatedArticles":[{"id":1700,"title":"Multiple sclerosis","link":"/articles/multiple-sclerosis?lang=us"},{"id":8614,"title":"Neurotoxoplasmosis","link":"/articles/neurotoxoplasmosis?lang=us"},{"id":1032,"title":"Lymphomas of the central nervous system","link":"/articles/lymphomas-of-the-central-nervous-system?lang=us"},{"id":4910,"title":"Glioblastoma, IDH-wildtype","link":"/articles/glioblastoma-idh-wildtype?lang=us"},{"id":38148,"title":"Multifocal glioblastoma","link":"/articles/multifocal-glioblastoma?lang=us"}],"alsoUsedIn":[],"stem":"\u003cp\u003eA 60-year-old man, previously well, presents with three peripherally enhancing, centrally non-enhancing, cerebral lesions. Two are in the white matter of the frontal lobe, and another is in the anterior body of the\u0026nbsp;corpus callosum. Which of the following is the most likely diagnosis?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/507"}],"attemptsPercentages":[{"alternativeId":"2541","percentage":28},{"alternativeId":"2543","percentage":32},{"alternativeId":"2544","percentage":15},{"alternativeId":"2545","percentage":12},{"alternativeId":"2542","percentage":13}],"promptToLogin":false,"questionManager":false,"articleId":"brain-metastases"}