Brodie abscess

Changed by Ayush Goel, 11 Nov 2014

Updates to Article Attributes

Body was changed:

A Brodie abscess refers to an abscess related to focus of chronic osteomyelitis in a bone. Unfortunately, there is no reliable way radiographically to exclude a focus of osteomyelitis. It has a protean radiographic appearance and can occur at any location and in a patient of any age. It might or might not be expansile, have a sclerotic or nonsclerotic border, or have associated periostitis. 

Demographics and clinical presentation

Typically these present in children, more frequently in boys. 

Pathology

Organism 
  • S. aureus (most common); cultures often negative
Location

It has a predilection for ends (metaphysis) of tubular bones:

  • proximal/distal tibial metaphysis (most common)
  • carpal and tarsal bones

Rarely traversing the open growth plate; epiphysis (in children and infants)/

Radiographic features

Plain film
  • lytic lesion often in an oval configuration that is oriented along the long axis of the bone
  • surrounded by thick dense rim of reactive sclerosis that fades imperceptibly into surrounding bone
  • lucent tortuous channel extending toward growth plate prior to physeal closure (pathognomonic(pathognomonic)
  • periosteal new-bone formation
  • +/- adjacent soft-tissue swelling
  • may persist for many months
  • -<p>A <strong>Brodie abscess</strong> refers to an <a href="/articles/abscess">abscess</a> related to focus of chronic <a href="/articles/osteomyelitis">osteomyelitis</a> in a bone. Unfortunately, there is no reliable way radiographically to exclude a focus of osteomyelitis. It has a protean radiographic appearance and can occur at any location and in a patient of any age. It might or might not be expansile, have a sclerotic or nonsclerotic border, or have associated periostitis. </p><h4>Demographics and clinical presentation</h4><p>Typically these present in children, more frequently in boys. </p><h4>Pathology</h4><h5>Organism </h5><ul><li>
  • +<p><strong>Brodie abscess</strong> refers to an <a href="/articles/abscess">abscess</a> related to focus of chronic <a href="/articles/osteomyelitis">osteomyelitis</a> in a bone. Unfortunately, there is no reliable way radiographically to exclude a focus of osteomyelitis. It has a protean radiographic appearance and can occur at any location and in a patient of any age. It might or might not be expansile, have a sclerotic or nonsclerotic border, or have associated periostitis. </p><h4>Demographics and clinical presentation</h4><p>Typically these present in children, more frequently in boys. </p><h4>Pathology</h4><h5>Organism </h5><ul><li>
  • -</ul><p>Rarely traversing the open growth plate; epiphysis (in children and infants)/</p><h4>Radiographic features</h4><h5>Plain film</h5><ul>
  • +</ul><p>Rarely traversing the open growth plate; epiphysis (in children and infants)</p><h4>Radiographic features</h4><h5>Plain film</h5><ul>
  • -<li>lucent tortuous channel extending toward growth plate prior to physeal closure (<strong>pathognomonic</strong>)</li>
  • +<li>lucent tortuous channel extending toward growth plate prior to physeal closure (pathognomonic)</li>

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