Carney triad
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- Micro-X Ltd, Shareholder (ongoing)
Updates to Article Attributes
Carney triad is a rare syndrome defined by the coexistence of three tumours:
-
initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal paragangliomas 1
In most cases, only 2 of the 3 tumours are present at the time of diagnosis, with the most common combination being GIST and pulmonary chondromas. Although not considered part of the triad, there is an increased incidence of adrenocortical adenoma. It typically affects young people. No underlying genetic mutation has been identified.
Terminology
It is not to be confused with the related Carney-Stratakis syndrome, or the unrelated Carney complex.
Memory tip:
Itit may be helpful to associate "T" in GIST with Carney Triad; "X" in MyXoma can be associated with Carney CompleX.
History and etymology
First described by J Aidan Carney, an American professor of pathology, and colleagues in 1977 5.
-<a href="/articles/paraganglioma-1">extra-adrenal paraganglioma</a><ul><li>initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal <a href="/articles/paraganglioma-1">paragangliomas</a> <sup>1</sup>-</li></ul>- +<p><a href="/articles/paraganglioma-1">extra-adrenal paraganglioma</a></p>
- +<ul><li><p>initially, only functioning extra-adrenal paragangliomas were included, but subsequent work includes non-functioning extra-adrenal <a href="/articles/paraganglioma-1">paragangliomas</a> <sup>1</sup></p></li></ul>
-<li>-<a href="/articles/gastrointestinal-stromal-tumour-1">gastric gastrointestinal stromal tumours</a><a href="/articles/gastrointestinal-stromal-tumour-1"> (GIST)</a>-</li>-<li><a href="/articles/pulmonary-chondroma">pulmonary chondroma</a></li>-</ul><p>In most cases, only 2 of the 3 tumours are present at the time of diagnosis, with the most common combination being GIST and pulmonary chondromas. Although not considered part of the triad, there is an increased incidence of adrenocortical adenoma. It typically affects young people. No underlying genetic mutation has been identified.</p><h4>Terminology</h4><p>It is not to be confused with the related <a href="/articles/carney-stratakis-syndrome-1">Carney-Stratakis syndrome</a>, or the unrelated <a href="/articles/carney-complex">Carney complex</a>.</p><ul><li>Memory tip : It may be helpful to associate "<strong>T"</strong> in GIS<strong>T </strong>with Carney <strong>T</strong>riad ; "<strong>X" </strong>in My<strong>X</strong>oma can be associated with <a title="Carney CompleX." href="/articles/carney-complex">Carney Comple<strong>X</strong></a>.</li></ul><h4>History and etymology</h4><p>First described by <strong>J Aidan Carney</strong>, an American professor of pathology, and colleagues in 1977 <sup>5</sup>.</p>- +<li><p><a href="/articles/gastrointestinal-stromal-tumour-1">gastric gastrointestinal stromal tumours (GIST)</a></p></li>
- +<li><p><a href="/articles/pulmonary-chondroma">pulmonary chondroma</a></p></li>
- +</ul><p>In most cases, only 2 of the 3 tumours are present at the time of diagnosis, with the most common combination being GIST and pulmonary chondromas. Although not considered part of the triad, there is an increased incidence of adrenocortical adenoma. It typically affects young people. No underlying genetic mutation has been identified.</p><h4>Terminology</h4><p>It is not to be confused with the related <a href="/articles/carney-stratakis-syndrome-1">Carney-Stratakis syndrome</a>, or the unrelated <a href="/articles/carney-complex">Carney complex</a>.</p><ul><li><p>Memory tip: it may be helpful to associate "<strong>T"</strong> in GIS<strong>T </strong>with Carney <strong>T</strong>riad; "<strong>X" </strong>in My<strong>X</strong>oma can be associated with <a href="/articles/carney-complex" title="Carney CompleX.">Carney Comple<strong>X</strong></a></p></li></ul><h4>History and etymology</h4><p>First described by <strong>J Aidan Carney</strong>, an American professor of pathology, and colleagues in 1977 <sup>5</sup>.</p>
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