Cavum septum pellucidum

Changed by Tim Luijkx, 2 Sep 2014

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The cavum septum pellucidum (CSP) is a normal variant CSF space between the leaflets of the septum pellucidum. It is sometimes called the fifth ventricle

Epidemiology

A CSP is present in 100% of fetuses, but over 85% of them fuse by 3-6 months of age meaning that a CSP is present in ~15% of the population.  

Gross anatomy

The CSP commonly occurs, and is often confused, with the more posterior cavum vergae by the, which is situated posterior to the anterior columns of the fornix. During development, these spaces obliterate postero-anteriorly - the cavum vergae followed by the cavum septum pellucidum - and it is not uncommon butthat both of these occur together. 

Boundaries 1
  • anteriorlyanterior - genu of the corpus callosum
  • superiorlysuperior - body of the corpus callosum
  • posteriorlyposterior - anterior limb and pillars of the fornix
  • inferiorlyinferior - anterior commissure and the rostrum of the corpus callosum
  • laterallylateral - leaflets of the septum pellucidum

Related pathology

It has been loosely associated with 3-5:

  • schizophrenia
  • post-traumatic stress disorder
  • chronic brain trauma

However, an absent cavum septum pellucidumin in antenatal imaging is a concerning feature and is associated with significant CNS anomalies 6.

Differential diagnosis

  • -<p>The <strong>cavum septum pellucidum (CSP) </strong>is a normal variant CSF space between the leaflets of the septum pellucidum. It is sometimes called the <strong>fifth ventricle</strong>. </p><h4>Epidemiology</h4><p>A CSP is present in 100% of fetuses, but over 85% of them fuse by 3-6 months of age meaning that a CSP is present in ~15% of the population.  </p><h4>Gross anatomy</h4><p>The CSP commonly occurs, and is confused, with the more posterior <a href="/articles/cavum-vergae">cavum vergae</a> by the anterior columns of the fornix. During development, these spaces obliterate postero-anteriorly - the cavum vergae followed by the cavum septum pellucidum - and it is not uncommon but both of these occur together. </p><h5>Boundaries <sup>1</sup>
  • +<p>The <strong>cavum septum pellucidum (CSP) </strong>is a normal variant CSF space between the leaflets of the septum pellucidum. It is sometimes called the <strong>fifth ventricle</strong>. </p><h4>Epidemiology</h4><p>A CSP is present in 100% of fetuses, but over 85% of them fuse by 3-6 months of age meaning that a CSP is present in ~15% of the population.  </p><h4>Gross anatomy</h4><p>The CSP commonly occurs, and is often confused with the <a href="/articles/cavum-vergae">cavum vergae</a>, which is situated posterior to the anterior columns of the fornix. During development, these spaces obliterate postero-anteriorly - the cavum vergae followed by the cavum septum pellucidum - and it is not uncommon that both occur together. </p><h5>Boundaries <sup>1</sup>
  • -<li>anteriorly - genu of the corpus callosum</li>
  • -<li>superiorly - body of the corpus callosum</li>
  • -<li>posteriorly - anterior limb and pillars of the fornix</li>
  • -<li>inferiorly - anterior commissure and the rostrum of the corpus callosum</li>
  • -<li>laterally - leaflets of the septum pellucidum</li>
  • +<li>anterior - genu of the corpus callosum</li>
  • +<li>superior - body of the corpus callosum</li>
  • +<li>posterior - anterior limb and pillars of the fornix</li>
  • +<li>inferior - anterior commissure and the rostrum of the corpus callosum</li>
  • +<li>lateral - leaflets of the septum pellucidum</li>
  • -</ul><p>However, an <a href="/articles/absent-cavum-septum-pellucidum">absent cavum septum pellucidum </a>in <strong>antenatal imaging</strong> is a concerning feature and is associated with significant CNS anomalies <sup>6</sup>.</p><h4>Differential diagnosis</h4><ul>
  • +</ul><p>However, an <a href="/articles/absent-cavum-septum-pellucidum">absent cavum septum pellucidum</a> in <strong>antenatal imaging</strong> is a concerning feature and is associated with significant CNS anomalies <sup>6</sup>.</p><h4>Differential diagnosis</h4><ul>

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