Cerebral small vessel disease
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Synonym Attributes
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Leukoaraiosis (from the Greek: leuko=white and araiosis=rarefaction) is a term given to areas of white matter low attenuation (WMLA) in the brain 1. It is more appropriately termed ischemic demyelination. They are commonly observed on brain CT scans of demented patients, particularly those with vascular dementia. They have also been reported to be present in some 'normal' elderly people.
Pathology
It results from arteriosclerotic changes in the deep penetrating vessels supplying the deep white matter and periventricular regions that lack collateral supply. Lacunar infarcts in the basal ganglia occur due to the same reason. Histology from these lesions show atrophy of axons and decreased myelin.
-<p><strong>Leukoaraiosis</strong> (from the Greek: leuko=white and araiosis=rarefaction) is a term given to areas of <a href="/articles/white-matter-low-attenuation-wmla" title="white matter low attenuation (WMLA)">white matter low attenuation (WMLA)</a> in the brain <sup>1</sup>. They are commonly observed on brain CT scans of demented patients, particularly those with vascular dementia. They have also been reported to be present in some 'normal' elderly people. </p>- +<p><strong>Leukoaraiosis</strong> (from the Greek: leuko=white and araiosis=rarefaction) is a term given to areas of <a href="/articles/white-matter-low-attenuation-wmla">white matter low attenuation (WMLA)</a> in the brain <sup>1</sup>. It is more appropriately termed <strong>ischemic demyelination</strong>. They are commonly observed on brain CT scans of demented patients, particularly those with vascular dementia. They have also been reported to be present in some 'normal' elderly people.</p><h4>Pathology</h4><p>It results from arteriosclerotic changes in the deep penetrating vessels supplying the deep white matter and <span style="line-height:1.6em">periventricular regions </span><span style="line-height:1.6em">that lack collateral supply. Lacunar infarcts in the basal ganglia occur due to the same reason. Histology from these lesions show atrophy of axons and decreased myelin.</span></p><p> </p>
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