Question 819
{"accessible":true,"alternatives":[{"id":4145,"text":"cortical laminar necrosis"},{"id":4146,"text":"Creutzfeldt-Jakob disease"},{"id":4147,"text":"gliomatosis cerebri"},{"id":4148,"text":"herpes encephalitis"},{"id":4149,"text":"post-epilepsy change"}],"archived":false,"correctAlternativeId":4146,"explanation":"\u003cp\u003eThere are very few differential diagnoses of this pattern of gyriform\u0026nbsp;restricted diffusion in the absence of an acute event and lack of any underlying known systemic disease. Creutzfeldt-Jakob disease (CJD) is by far the most likely diagnosis, in this instance\u0026nbsp;later confirmed by biopsy.\u0026nbsp;\u003c/p\u003e","id":819,"imageUrl":"https://prod-images-static.radiopaedia.org/multiple_choice_questions/925/images-for-mcqs-1__5__big_gallery.jpeg","imageAttribution":{"kind":"case","rID":53588},"imageAttributionCaseInfo":{"title":"Creutzfeldt-Jakob Disease","contributor_name":"Mandakini Siwach","contributor_param":"msiwach","case_rid":53588,"case_param":"creutzfeldt-jakob-disease-6"},"firstQuestionPath":"/questions/819","nextQuestionPath":null,"relatedArticles":[{"id":1410,"title":"Herpes simplex encephalitis","link":"/articles/herpes-simplex-encephalitis?lang=us"},{"id":7269,"title":"Creutzfeldt-Jakob disease","link":"/articles/creutzfeldt-jakob-disease?lang=us"},{"id":1389,"title":"Gliomatosis cerebri","link":"/articles/gliomatosis-cerebri?lang=us"}],"alsoUsedIn":[{"id":502,"kind":"Course","title":"Neurodegenerative Learning Pathway - page 502","link":"https://radiopaedia.org/courses/neurodegenerative-learning-pathway/pages/502"},{"id":784,"kind":"Course","title":"Stroke Learning Pathway - page 784","link":"https://radiopaedia.org/courses/stroke-learning-pathway/pages/784"},{"id":1065,"kind":"Course","title":"Neurodegenerative Learning Pathway - page 1065","link":"https://radiopaedia.org/courses/neurodegenerative-learning-pathway/pages/1065"},{"id":2121,"kind":"Course","title":"Stroke Learning Pathway - peer review - page 2121","link":"https://radiopaedia.org/courses/stroke-learning-pathway-peer-review/pages/2121"}],"stem":"\u003cp\u003eA 50-year-old man presents with deteriorating memory over the last 3 months. He has a history of\u0026nbsp;right eye rhabdomyosarcoma treated with surgery. No other known illnesses. He is investigated with an MRI of the brain. What is the most likely diagnosis?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/819"}],"attemptsPercentages":[{"alternativeId":"4147","percentage":9},{"alternativeId":"4148","percentage":4},{"alternativeId":"4149","percentage":5},{"alternativeId":"4146","percentage":65},{"alternativeId":"4145","percentage":17}],"promptToLogin":false,"questionManager":false,"articleId":"cortical-laminar-necrosis"}