Cotswolds-modified Ann Arbor classification
Updates to Article Attributes
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was changed:
The Cotsworlds-modified Ann Arbor classification is a lymphoma staging classification system for both Hodgkin lymphoma and non-Hodgkin lymphoma.
They came about in 1988 following recommended modifications to the Ann Arbor staging system after a meeting in Cotswold, England and are as follows:
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stage I: one nodal group or lymphoid organ (e.g. spleen or thymus)
- stage IE: one extranodal site
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stage II: two or more nodal groups, same side of diaphragm
- stage IIE: localised extranodal site with stage II criteria, both on the same side of the diaphragm
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stage III: nodal groups on both sides of the diaphragm
- stage IIIS(1): with splenic involvement
- stage IIIE(2): with localised extranodal site
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stage IIISE:
:both
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stage IV: disseminated involvement of one or more extralymphatic organ (e.g. lung, bone)
+/-with or without any nodal involvement
Additional stagingsub-staging variables:
- A: asymptomatic
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B: presence of B symptoms
(fever(including fever, night sweats and weight loss of over 10% of body weight over 6 months) - X: bulky nodal disease: nodal mass >1/3 of intrathoracic diameter or 10 cm in dimension
-<strong>stage IIISE</strong>: both</li>- +<strong>stage IIISE:</strong> both</li>
-<strong>stage IV:</strong> disseminated involvement of one or more extralymphatic organ (e.g. lung, bone) +/- any nodal involvement</li>-</ul><p>Additional staging variables:</p><ul>- +<strong>stage IV:</strong> disseminated involvement of one or more extralymphatic organ (e.g. lung, bone) with or without any nodal involvement</li>
- +</ul><p>Additional sub-staging variables:</p><ul>
-<strong>B:</strong> presence of B symptoms (fever, night sweats and weight loss)</li>- +<strong>B:</strong> presence of B symptoms (including fever, night sweats and weight loss of over 10% of body weight over 6 months)</li>