Cotswolds-modified Ann Arbor classification
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The CotsworldsCotswolds-modified Ann Arbor classification is a lymphoma staging classification system for both Hodgkin lymphoma and non-Hodgkin lymphoma.
They came about in 1988 following recommended modifications to the Ann Arbor staging system after a meeting in Cotswold, England and are as follows:
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stage I: one nodal group or lymphoid organ (e.g. spleen or thymus)
- stage IE: one extranodal site
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stage II: two or more nodal groups, same side of the diaphragm
- stage IIE: localised extranodal site with stage II criteria, both on the same side of the diaphragm
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stage III: nodal groups on both sides of the diaphragm
- stage IIIS(1): with splenic involvement
- stage IIIE(2): with localised extranodal site
- stage IIISE: both
- stage IV: disseminated involvement of one or more extralymphatic organ (e.g. lung, bone) with or without any nodal involvement
Additional sub-staging variables:
- A: asymptomatic
- B: presence of B symptoms (including fever, night sweats and weight loss of over 10% of body weight over 6 months)
- X: bulky nodal disease: nodal mass >1/3 of intrathoracic diameter or 10 cm in dimension
-<p>The <strong>Cotsworlds-modified Ann Arbor classification</strong> is a <a href="/articles/lymphoma-staging-1">lymphoma staging</a> classification system for both <a href="/articles/hodgkin-lymphoma">Hodgkin lymphoma</a> and <a href="/articles/non-hodgkin-lymphoma">non-Hodgkin lymphoma</a>.</p><p>They came about in 1988 following recommended modifications to the Ann Arbor staging system after a meeting in Cotswold, England and are as follows:</p><ul>- +<p>The <strong>Cotswolds-modified Ann Arbor classification</strong> is a <a href="/articles/lymphoma-staging-1">lymphoma staging</a> classification system for both <a href="/articles/hodgkin-lymphoma">Hodgkin lymphoma</a> and <a href="/articles/non-hodgkin-lymphoma">non-Hodgkin lymphoma</a>.</p><p>They came about in 1988 following recommended modifications to the Ann Arbor staging system after a meeting in Cotswold, England and are as follows:</p><ul>
-<strong>stage II:</strong> two or more nodal groups, same side of diaphragm<ul><li>- +<strong>stage II:</strong> two or more nodal groups, same side of the diaphragm<ul><li>
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