Deterministic effects

Changed by Victor Tang, 7 Apr 2019

Updates to Article Attributes

Body was changed:

Deterministic effects describe a cause and effect relationship between radiation and certain side-effects. They are also called non-stochastic effects to contrast with chance-like stochastic effects (e.g. cancer induction).

Deterministic effects have a threshold below which the effect does not occur. The threshold may be very low and may vary from person to person. However, once the threshold has been exceeded, the severity of an effect increases with dose.

Examples of deterministic effects (doses are given as absorbed dose):

  • skin erythema: 2-5 Gy
  • irreversible skin damage: 20-40 Gy
  • hair loss: 2-5 Gy
  • sterility: 2-3 Gy
  • cataracts: 50.5 Gy. Note: significantly lowered threshold of 5Gy to 0.5Gy in the latest ICRP 118 1.
  • lethality (whole body): 3-5 Gy
  • fetal abnormality: 0.1-0.5 Gy
  • -<li>cataracts: 5 Gy</li>
  • +<li>cataracts: 0.5 Gy. <em>Note: significantly lowered threshold of 5Gy to 0.5Gy in the latest ICRP 118 <sup>1</sup>. </em>
  • +</li>

References changed:

  • 1. W.E. Bolch, G. Dietze, N. Petoussi-Henss, M. Zankl. Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures:. (2015) Annals of the ICRP. 44 (1 Suppl): 91-111. <a href="https://doi.org/10.1177/0146645314562320">doi:10.1177/0146645314562320</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/25816263">Pubmed</a> <span class="ref_v4"></span>
  • 1. W.E. Bolch, G. Dietze, N. Petoussi-Henss, M. Zankl. Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures:. (2015) Annals of the ICRP. 44 (1 Suppl): 91-111. <a href="https://doi.org/10.1177/0146645314562320">doi:10.1177/0146645314562320</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/25816263">Pubmed</a> <span class="ref_v4"></span>
  • 2. Penelope Allisy-Roberts, Jerry R. Williams. Farr's Physics for Medical Imaging. <a href="https://books.google.co.uk/books?vid=ISBN9780702028441">ISBN: 9780702028441</a><span class="ref_v4"></span>
  • 3. Philip Palin Dendy, Brian Heaton. Physics for Diagnostic Radiology, Third Edition. <a href="https://books.google.co.uk/books?vid=ISBN9780750305914">ISBN: 9780750305914</a><span class="ref_v4"></span>
  • 1. Penelope Allisy-Roberts, Jerry R. Williams. Farr's Physics for Medical Imaging. <a href="https://books.google.co.uk/books?vid=ISBN9780702028441">ISBN: 9780702028441</a><span class="ref_v4"></span>
  • 1. Schmoldt A, Benthe HF, Haberland G. Digitoxin metabolism by rat liver microsomes. (1975) Biochemical pharmacology. 24 (17): 1639-41. <a href="https://www.ncbi.nlm.nih.gov/pubmed/10">Pubmed</a> <span class="ref_v4"></span>
  • 2. Philip Palin Dendy, Brian Heaton. Physics for Diagnostic Radiology, Third Edition. <a href="https://books.google.co.uk/books?vid=ISBN9780750305914">ISBN: 9780750305914</a><span class="ref_v4"></span>

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