Question 2138
{"accessible":false,"alternatives":[{"id":10618,"text":"tumor expands the pons"},{"id":10619,"text":"tumor extends around the basilar artery"},{"id":10620,"text":"tumor extends into thalamus"},{"id":10621,"text":"tumor involves ventral pons"},{"id":10622,"text":"tumor is exophytic"}],"archived":false,"correctAlternativeId":10622,"explanation":"\u003cp\u003e\u003ca href=\"/articles/diffuse-midline-glioma-h3-k27m-mutant\"\u003eDiffuse midline glioma (H3 K27M mutant)\u003c/a\u003e\u0026nbsp;is what used to be classically described as a diffuse\u0026nbsp;intrinsic brainstem glioma (that diagnosis is no longer present in the WHO classification of brain tumors).\u003c/p\u003e\u003cp\u003eThese tumors are centered in the ventral pons and usually expand the pons, often around the basilar artery. They may extend upwards into the thalamus.\u003c/p\u003e\u003cp\u003eExophytic tumors are usually low-grade tumors that do not have this mutation and their prognosis is much better.\u003c/p\u003e","id":2138,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/2590","nextQuestionPath":"/articles/diffuse-midline-glioma-h3-k27-altered/questions/715","relatedArticles":[{"id":6491,"title":"Diffuse brainstem glioma (historical)","link":"/articles/diffuse-brainstem-glioma-historical?lang=us"}],"alsoUsedIn":[{"id":992,"kind":"Course","title":"2021 Virtual Conference Private Use - page 992","link":"https://radiopaedia.org/courses/2021-virtual-conference-private-use/pages/992"},{"id":992,"kind":"Course","title":"Radiopaedia 2021 - isoCME - page 992","link":"https://radiopaedia.org/courses/radiopaedia-2021-isocme/pages/992"},{"id":992,"kind":"Course","title":"2022 Virtual Conference Private Use - page 992","link":"https://radiopaedia.org/courses/2022-virtual-conference-private-use/pages/992"},{"id":970,"kind":"RestrictedPage","title":"Page 970 (in no courses)","link":"https://radiopaedia.org/admin/restricted_pages/970"},{"id":955,"kind":"RestrictedPage","title":"Page 955 (in no courses)","link":"https://radiopaedia.org/admin/restricted_pages/955"},{"id":1,"kind":"LiveSchedule","title":"1","link":"https://radiopaedia.org/admin/live_schedules/1"},{"id":53,"kind":"LiveSchedule","title":"53","link":"https://radiopaedia.org/admin/live_schedules/53"},{"id":945,"kind":"Course","title":"Radiopaedia 2021 - isoCME - page 945","link":"https://radiopaedia.org/courses/radiopaedia-2021-isocme/pages/945"},{"id":945,"kind":"Course","title":"2021 Virtual Conference Private Use - page 945","link":"https://radiopaedia.org/courses/2021-virtual-conference-private-use/pages/945"},{"id":945,"kind":"Course","title":"Paediatric Lectures - page 945","link":"https://radiopaedia.org/courses/paediatric-lectures/pages/945"}],"stem":"\u003cp\u003eA child presents with a prolonged headache and VI nerve palsy. An MRI is performed that demonstrates a brainstem tumor. The radiologist is convinced that this is a diffuse midline glioma with the H3 K27M mutation. Which of the following imaging findings, would be \u003cstrong\u003eUNEXPECTED\u003c/strong\u003e\u0026nbsp;for this tumor type?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/2138"}],"attemptsPercentages":[{"alternativeId":"10622","percentage":69},{"alternativeId":"10620","percentage":14},{"alternativeId":"10618","percentage":4},{"alternativeId":"10619","percentage":8},{"alternativeId":"10621","percentage":5}],"promptToLogin":false,"questionManager":false,"articleId":"diffuse-midline-glioma-h3-k27-altered"}