Disseminated histoplasmosis
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- updated 13 Jan 2023:
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Disseminated histoplasmosis, also known as progressive disseminated histoplasmosis, is a subtypesevere form of histoplasmosis infection typically seen in immunosuppresed patients, especially in the setting of HIV infection with less than 150 cells/μL CD4. It is a severe formresults from haematogeneous dissemination of the infection that can involve multiple organs and systems and associates a high mortality1.
Terminology
Although it is sometimes referred as extrapulmonary histoplasmosis, lung involvement is one of the commonest manifestations of this condition.
-<p><strong>Disseminated histoplasmosis</strong>, also known as<strong> progressive disseminated histoplasmosis</strong>, is a subtype of <a href="/articles/histoplasmosis" title="Histoplasmosis">histoplasmosis infection</a> typically seen in immunosuppresed patients, especially in the setting of <a href="/articles/hivaids" title="HIV">HIV infection</a> with less than 150 cells/μL CD4. It is a severe form of the infection that can involve multiple organs and systems and associates a high mortality<sup>1</sup>.</p>- +<p><strong>Disseminated histoplasmosis</strong>, also known as<strong> progressive disseminated histoplasmosis</strong>, is a severe form of <a href="/articles/histoplasmosis" title="Histoplasmosis">histoplasmosis infection</a> typically seen in immunosuppresed patients, especially in the setting of <a href="/articles/hivaids" title="HIV">HIV infection</a> with less than 150 cells/μL CD4. It results from haematogeneous dissemination of the infection that can involve multiple organs and systems and associates a high mortality<sup>1</sup>.</p><h4>Terminology</h4><p>Although it is sometimes referred as extrapulmonary histoplasmosis, lung involvement is one of the commonest manifestations of this condition. </p>
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