Dual-energy CT (clinical applications)

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Dual-energy CT or multispectral CT is becoming increasingly more common in clinical practice due to the rapid rise in computer technology and expanding literature exhibiting vast advantages over conventional single energy CT.

Clinical applications

The clinical practice, adaptation and techniques of dual-energy CT is broken into individual articles:

virtual non-contrast imaging
vascular, f. ex.
- automated bone removal in CT angiography ²
- decrease metal device artifact⁷
- detection of endoleaks⁷
- blood pool imaging ²
  - detection of pulmonary embolism
  - detection of myocardial ischaemia
urinary system
- characterisation of renal stones ²
- characterisation of renal cysts and masses ^2-⁴
female breast
- identification of silicone leaks from breast implants ²
musculoskeletal
- detection of bone marrow edema
- detection and quantification of urate crystals in gout
abdominal imaging
- pancreatic diseases ⁵
thoracic imaging

-Dual-energy CT or multispectral CT is becoming increasingly more common in clinical practice due to the rapid rise in computer technology and expanding literature exhibiting vast advantages over conventional single energy CT. <h4>Clinical applications</h4>The clinical practice, adaptation and techniques of <a title="Dual energy CT" href="/articles/dual-energy-ct-2">dual-energy CT </a>is broken into individual articles:<ul>
+Dual-energy CT or multispectral CT is becoming increasingly more common in clinical practice due to the rapid rise in computer technology and expanding literature exhibiting vast advantages over conventional single energy CT. <h4>Clinical applications</h4>The clinical practice, adaptation and techniques of <a href="/articles/dual-energy-ct-2">dual-energy CT </a>is broken into individual articles:<ul>
+<li>decrease metal device artifact7
+</li>
+<li>detection of endoleaks7 </li>
~~-female breast<ul><li>identification of silicone leaks from <a href="/articles/breast-implants">breast implants</a> 2~~
~~-</li></ul>~~
+female breast<ul>
+<li>identification of silicone leaks from <a href="/articles/breast-implants">breast implants</a> 2
+</li>
+<li>improved tumour conspicuity of breast cancers relative to conventional CT, with potential determination of prognostic biomarkers such as ER and PR status6
+</li>
+</ul>
+<li>reduction of metal artifact7
+</li>
+<li>thoracic imaging<ul>
+<li>detection of pulmonary thromboembolism. Structural as well as functional information is obtained through iodine maps of pulmonary perfusion7
+</li>
+<li>assessment of a solitary pulmonary nodule to determine malignancy status7,8
+</li>
+</ul>
+</li>

References changed:

6. Moon J, Choi B, Baek H et al. Comprehensive Analyses with Radiological and Biological Markers of Breast Cancer on Contrast-Enhanced Chest CT: A Single Center Experience Using Dual-Layer Spectral Detector CT. Eur Radiol. 2020;30(5):2782-90. <a href="https://doi.org/10.1007/s00330-019-06615-9">doi:10.1007/s00330-019-06615-9</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/32025829">Pubmed</a>
7. Cicero G, Ascenti G, Albrecht M et al. Extra-Abdominal Dual-Energy CT Applications: A Comprehensive Overview. Radiol Med. 2020;125(4):384-97. <a href="https://doi.org/10.1007/s11547-019-01126-5">doi:10.1007/s11547-019-01126-5</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/31925704">Pubmed</a>
8. Wu L, Cao G, Zhao L et al. Spectral CT Analysis of Solitary Pulmonary Nodules for Differentiating Malignancy from Benignancy: The Value of Iodine Concentration Spatial Distribution Difference. Biomed Res Int. 2018;2018:4830659. <a href="https://doi.org/10.1155/2018/4830659">doi:10.1155/2018/4830659</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/30627561">Pubmed</a>

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Dual-energy CT (clinical applications)

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