Expanded treatment in cerebral infarction (eTICI) score

Changed by Rohit Sharma, 10 Feb 2024
Disclosures - updated 18 Aug 2023: Nothing to disclose

Updates to Article Attributes

Title was changed:
Expanded treatment in cerebral ischemiainfarction (eTICI) score
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The expanded treatment in cerebral infarction (eTICI)score is is a modified from the modified treatment in cerebral infarction (mTICI) and and thrombolysis in cerebral infarction (TICI) scales scales. It was published by the HERMES investigators in 20191.

Using modified Rankin scale (mRs) shift shift at 90 days as the outcome measure, the investigators found a significant difference in outcomes for patients with partial recanalizationrecanalisation after endovascular clot retrieval between between those with reperfusion of 50–66%, 67–89% and 90-90% in addition to those previously defined by mTICI.

Classification

  • grade 0: no perfusion noted (0% reperfusion)

  • grade 1: reduction reduction in thrombus but without any resultant filling of distal arterial branches

  • grade 2

    • grade 2a: reperfusion of 1-49% of the territory

    • grade 2b50: reperfusion of 50–66% of the territory

    • grade 2b67: reperfusion of 67–89% of the territory

    • grade 2c: extensive reperfusion of 90–99% of the territory

  • grade 3: complete complete or full reperfusion (100% reperfusion)

Important points

  • Inter

    inter-rater agreement is the most difficult between eTICI grade 2a and 2b, however with adequate angiographic views agreement of 92% (κ=0.83, p<0.001) was reported by the investigators1

  • eTICI appears to be an independent predictor of 90-day mRS

See also

  • -<p>The <strong>expanded treatment in cerebral infarction (eTICI</strong>) <strong>score</strong> is a modified from the <a href="/articles/modified-treatment-in-cerebral-ischaemia-mtici-score">modified treatment in cerebral infarction (mTICI)</a> and <a href="/articles/thrombolysis-in-cerebral-infarction-tici-scale">thrombolysis in cerebral infarction (TICI)</a> scales. It was published by the HERMES investigators in 2019<sup>1</sup>.</p><p>Using <a href="/articles/modified-rankin-scale">modified Rankin scale (mRs)</a> shift at 90 days as the outcome measure, the investigators found a significant difference in outcomes for patients with partial recanalization after <a href="/articles/mechanical-thombectomy">mechanical thrombectomy</a> between those with reperfusion of 50–66%, 67–89% and 90-90% in addition to those previously defined by mTICI.</p><h4>Classification</h4><ul>
  • -<li>grade 0: no perfusion noted (0% reperfusion)</li>
  • -<li>grade 1: reduction in thrombus but without any resultant filling of distal arterial branches</li>
  • -<li>grade 2<ul>
  • -<li>grade 2a: reperfusion of 1-49% of the territory</li>
  • -<li>grade 2b50: reperfusion of 50–66% of the territory</li>
  • -<li>grade 2b67: reperfusion of 67–89% of the territory</li>
  • -<li>grade 2c: extensive reperfusion of 90–99% of the territory</li>
  • +<p>The <strong>expanded treatment in cerebral infarction (eTICI</strong>)&nbsp;<strong>score</strong>&nbsp;is a modified from the <a href="/articles/modified-treatment-in-cerebral-infarction-mtici-score">modified treatment in cerebral infarction (mTICI)</a>&nbsp;and <a href="/articles/thrombolysis-in-cerebral-infarction-tici-scale">thrombolysis in cerebral infarction (TICI)</a>&nbsp;scales. It was published by the HERMES investigators in 2019 <sup>1</sup>.</p><p>Using <a href="/articles/modified-rankin-scale">modified Rankin scale (mRs)</a>&nbsp;shift at 90 days as the outcome measure, the investigators found a significant difference in outcomes for patients with partial recanalisation after <a href="/articles/endovascular-clot-retrieval-ecr" title="Endovascular clot retrieval (ECR)">endovascular clot retrieval</a>&nbsp;between those with reperfusion of 50–66%, 67–89% and 90-90% in addition to those previously defined by mTICI.</p><h4>Classification</h4><ul>
  • +<li><p>grade 0: no perfusion noted (0% reperfusion)</p></li>
  • +<li><p>grade 1:&nbsp;reduction in thrombus but without any resultant filling of distal arterial branches</p></li>
  • +<li>
  • +<p>grade 2</p>
  • +<ul>
  • +<li><p>grade 2a: reperfusion of 1-49% of the territory</p></li>
  • +<li><p>grade 2b50: reperfusion of 50–66% of the territory</p></li>
  • +<li><p>grade 2b67: reperfusion of 67–89% of the territory</p></li>
  • +<li><p>grade 2c: extensive reperfusion of 90–99% of the territory</p></li>
  • -<li>grade 3: complete or full reperfusion (100% reperfusion)</li>
  • +<li><p>grade 3:&nbsp;complete or full reperfusion (100% reperfusion)</p></li>
  • -<li>Inter-rater agreement is the most difficult between eTICI grade 2a and 2b, however with adequate angiographic views agreement of 92% (κ=0.83, p&lt;0.001) was reported by the investigators<sup>1</sup>
  • -</li>
  • -<li>eTICI appears to be an independent predictor of 90-day mRS</li>
  • -</ul><ul></ul>
  • +<li><p>inter-rater agreement is the most difficult between eTICI grade 2a and 2b, however with adequate angiographic views agreement of 92% (κ=0.83, p&lt;0.001) was reported by the investigators <sup>1</sup></p></li>
  • +<li><p>eTICI appears to be an independent predictor of 90-day mRS</p></li>
  • +</ul><h4>See also</h4><ul>
  • +<li><p><a href="/articles/thrombolysis-in-cerebral-infarction-tici-scale">thrombolysis in cerebral infarction (TICI) scale</a></p></li>
  • +<li><p><a href="/articles/modified-treatment-in-cerebral-infarction-mtici-score">modified treatment in cerebral infarction (mTICI) score</a></p></li>
  • +</ul>

Sections changed:

  • Classifications

Systems changed:

  • Vascular

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