Extra-adrenal myelolipoma
Updates to Article Attributes
Extra-adrenal myelolipomas occur outside the adrenal glands, with the most common sites being the retroperitoneum, thorax, and pelvis.
Epidemiology
The widespread application of modern imaging techniques has led to increase in the detection of extra-adrenal myelolipomas. The exact incidence is unknown.
Clinical presentation
The majority of patients are asymptomatic at the time of diagnosis, and lesions are discovered incidentally on imaging for alternative medical problems. They are found more commonly in women.
PathologyTreatment and prognosis
A fatty mass within the retroperitoneal space presents a diagnostic challenge as the differential diagnosis include angiomyolipoma, a retroperitoneal teratoma, and a well-differentiated liposarcoma. It is important to differentiate from extra-medullary hematopoiesis.
When When in doubt a biopsy should be performed. No treatment is necessary as it is a benign entity. Malignant degeneration has not been reported so far.
Differential diagnosis
-<p><strong>Extra-adrenal myelolipomas</strong> occur outside the adrenal glands, with the most common sites being the retroperitoneum, thorax, and pelvis. </p><h4>Epidemiology</h4><p>The widespread application of modern imaging techniques has led to increase in the detection of extra-adrenal myelolipomas. The exact incidence is unknown.</p><h4>Clinical presentation</h4><p>The majority of patients are asymptomatic at the time of diagnosis, and lesions are discovered incidentally on imaging for alternative medical problems. They are found more commonly in women.</p><h4>Pathology</h4><p>A fatty mass within the retroperitoneal space presents a diagnostic challenge as the differential diagnosis include angiomyolipoma, a retroperitoneal teratoma, and a well-differentiated liposarcoma. It is important to differentiate from extra-medullary hematopoiesis. </p><p>When in doubt a biopsy should be performed. No treatment is necessary as it is a benign entity. Malignant degeneration has not been reported so far.</p><h4> </h4>- +<p><strong>Extra-adrenal myelolipomas</strong> occur outside the adrenal glands, with the most common sites being the <a title="Retroperitoneum" href="/articles/retroperitoneum">retroperitoneum</a>, thorax, and pelvis. </p><h4>Epidemiology</h4><p>The widespread application of modern imaging techniques has led to increase in the detection of extra-adrenal myelolipomas. The exact incidence is unknown.</p><h4>Clinical presentation</h4><p>The majority of patients are asymptomatic at the time of diagnosis, and lesions are discovered incidentally on imaging for alternative medical problems. They are found more commonly in women.</p><h4>Treatment and prognosis</h4><p>A fatty mass within the retroperitoneal space presents a diagnostic challenge. When in doubt a biopsy should be performed. No treatment is necessary as it is a benign entity. Malignant degeneration has not been reported so far.</p><h4>Differential diagnosis</h4><ul>
- +<li><a href="/articles/angiomyolipoma">angiomyolipoma</a></li>
- +<li>retroperitoneal <a title="Teratoma" href="/articles/teratoma">teratoma</a>
- +</li>
- +<li><a href="/articles/retroperitoneal-liposarcoma-2">well-differentiated liposarcoma</a></li>
- +<li><a href="/articles/extramedullary-haematopoiesis">extramedullary hematopoiesis</a></li>
- +</ul>
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Image 1 CT (C+ portal venous phase) ( update )
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