Fetal anemia
Updates to Article Attributes
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was changed:
Fetal anaemia is a characterized by inadequate erythrocytes being delivered to the fetus and can result from many causes.
Pathology
Aetiology
- haemolytic disease of the newborn
- fetal infections
- haematopoetic abnomalities
- homozygous alpha thalassaemia 7
- syndromes
- tumours
Radiographic features
Ultrasound
General sonographic features include:
- evidence of fetal hepatomegaly and/or fetal splenomegaly
- effects of subsequent cardiovascular compromise
- development of hydrops fetalis
Doppler
- increase in fetal middle cerebral arterial (MCA) Doppler time average mean velocity (TAMV): may occur before precipitation of fetal hydrops
- increase in fetal middle cerebral arterial (MCA) Doppler peak systolic velocity (PSV): may occur before precipitation of fetal hydrops
- changes in fetal MCA Doppler are reported to have 88% sensitivity and
aan 82% specificity for detection of fetal anaemias
Fetal MRI
MRI can be used to detect fetal anemia 8 and some of it'sits sequellae. T1 and T2 relaxation times of relevant areas e.g. the umbilical vein's blood allow for detection.
Treatment and prognosis
Intra-uterine transfusion via the umbilical vein can be successfullysuccessful in selected cases. OverallThe overall prognosis will depend on underlying conditions and associations.
See also
-<li>changes in fetal MCA Doppler are reported to have 88% sensitivity and a 82% specificity for detection of fetal anaemias </li>-</ul><h5>Fetal MRI</h5><p>MRI can be used to detect fetal anemia <sup>8</sup> and some of it's sequellae. T1 and T2 relaxation times of relevant areas e.g. the umbilical vein's blood allow for detection.</p><h4>Treatment and prognosis</h4><p><a href="/articles/intra-uterine-transfusion">Intra-uterine transfusion</a> via the umbilical vein can be successfully in selected cases. Overall prognosis will depend on underlying conditions and associations. </p><h4>See also</h4><ul><li><a href="/articles/fetal-thrombocytopenia-1">fetal thrombocytopenia</a></li></ul>- +<li>changes in fetal MCA Doppler are reported to have 88% sensitivity and an 82% specificity for detection of fetal anaemias </li>
- +</ul><h5>Fetal MRI</h5><p>MRI can be used to detect fetal anemia <sup>8</sup> and some of its sequellae. T1 and T2 relaxation times of relevant areas e.g. the umbilical vein's blood allow for detection.</p><h4>Treatment and prognosis</h4><p><a href="/articles/intra-uterine-transfusion">Intra-uterine transfusion</a> via the umbilical vein can be successful in selected cases. The overall prognosis will depend on underlying conditions and associations. </p><h4>See also</h4><ul><li><a href="/articles/fetal-thrombocytopenia-1">fetal thrombocytopenia</a></li></ul>
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