Fibromatosis of the breast
Updates to Article Attributes
Body
was changed:
Fibromatosis of the breast(also known as an extra-abdominal desmoid tumour of the breast or mammary fibromatosis 4) is considered as a type of rare breast tumour. It is a non metastasising benign but locally invasive stromal tumour 4. However it can mimic more sinister types of breast cancer on both imaging and clinical findings 8.
Epidemiology
They account for only 0.2% of all breast tumours 9.
Clinical presentation
A desmoid tumour appears as a solitary, hard and painless nodule, which sometimes can be attached to the skin or to the pectoral muscle fascia.
Pathology
The entity is pathologically indistinguishable from fibromatosis occurring elsewhere in the body. The tumour has a with with a fibroblastic and myofibroblastic origin.
Associations
Recognised associations include:
- Gardner syndrome4,9
- saline or silicone breast implants4,9
- prior surgical trauma 4,9
Location
- while it can occur anywhere in the breast, lesions may tend to occur in close proximity to pectoral muscles
.
Radiographic features
Mammography
A spicutated irregular non calcified mass is considered the most common mammographic finding.
Breast ultrasound
Fibromatosis typically appears as a solid, spiculated or microlobulated, irregular hypo-echoic mass with straightening and tethering of Cooper ligaments, which is very difficult to differentiate from a malignant lesion
Breast MRI
Usually seen an irregular breast mass
-
T1:
:mammary fibromatosi may appear as ill-defined, hypo- to isointense masses -
T2:
:usually heterogeneously hyper-intense in signal -
T1 C+ (Gd):
:often show suspicious, slow enhancement after contrast administration
MRI is often useful to show chest wall involvement in selected cases prior to surgical planning.
Treatment and prognosis
Although it is a benign non metastasing tumour, it can be locally aggessive. Wide local excision with clear margins remains the treatment of choice 5. Recurrence Recurrence rates can be high, especially in those with positive margins. Recurrence Recurrence is less likely if a wide excision is performed and resection margins are made sure to be disease-free. Recurrences Recurrences are also often treated with radical excision, as the primary tumour12
See also
-<p><strong>Fibromatosis of the breast</strong> (also known as an <strong>extra-abdominal desmoid tumour of the breast </strong>or <strong>mammary fibromatosis </strong><sup>4</sup>) is considered as a type of rare <a href="/articles/breast-neoplasms" title="Breast neoplasm">breast tumour</a>. It is a non metastasising benign but locally invasive stromal tumour <sup>4</sup>. However it can mimic more sinister types of breast cancer on both imaging and clinical findings <sup>8</sup>.</p><h4>Epidemiology</h4><p>They account for only 0.2 % of all breast tumours <sup>9</sup>.</p><h4>Clinical presentation</h4><p>A desmoid tumour appears as a solitary, hard and painless nodule, which sometimes can be attached to the skin or to the pectoral muscle fascia.</p><h4>Pathology</h4><p>The entity is pathologically indistinguishable from <a href="/articles/fibromatosis" title="fibromatosis">fibromatosis </a>occurring elsewhere in the body. The tumour has a with a fibroblastic and myofibroblastic origin.</p><h5>Associations</h5><p>Recognised associations include</p><ul><li><a href="/articles/gardner_syndrome" title="Gardner syndrome">Gardner syndrome</a> <sup>4,9</sup></li><li>saline or silicone <a href="/articles/breast-implants" title="Breast implants">breast implants</a><sup><a href="/articles/breast-implants" title="Breast implants"> </a>4,9</sup></li><li>prior surgical trauma <sup>4,9</sup></li></ul><h5>Location</h5><ul><li>while it can occur anywhere in the breast, lesions may tend to occur in close proximity to pectoral muscles. </li></ul><h4>Radiographic features</h4><h5>Mammography</h5><p>A spicutated irregular non calcified mass is considered the most common mammographic finding.</p><h5>Breast ultrasound</h5><p>Fibromatosis typically appears as a solid, spiculated or microlobulated, irregular hypo-echoic mass with straightening and tethering of Cooper ligaments, which is very difficult to differentiate from a malignant lesion </p><h5>Breast MRI</h5><p>Usually seen an irregular breast mass</p><ul><li><strong>T1 </strong>: mammary fibromatosi may appear as ill-defined, hypo- to isointense masses</li><li><strong>T2</strong> : usually heterogeneously hyper-intense in signal</li><li><strong>C+ (Gd)</strong> : often show suspicious, slow enhancement after contrast administration </li></ul><p>MRI is often useful to show chest wall involvement in selected cases prior to surgical planning.</p><h4>Treatment and prognosis</h4><p>Although it is a benign non metastasing tumour, it can be locally aggessive. Wide local excision with clear margins remains the treatment of choice <sup>5</sup>. Recurrence rates can be high, especially in those with positive margins. Recurrence is less likely if a wide excision is performed and resection margins are made sure to be disease-free. Recurrences are also often treated with radical excision, as the primary tumour <sup>12</sup>.</p><h4>See also</h4><ul><li><a href="/articles/desmoid-tumour" title="desmoid tumour">desmoid tumour</a></li><li><a href="/articles/fibrosarcoma-of-the-breast" title="fibrosarcoma of the breast">fibrosarcoma of the breast</a></li></ul>- +<p><strong>Fibromatosis of the breast</strong> (also known as an <strong>extra-abdominal desmoid tumour of the breast </strong>or <strong>mammary fibromatosis </strong><sup>4</sup>) is considered as a type of rare <a href="/articles/breast-neoplasms">breast tumour</a>. It is a non metastasising benign but locally invasive stromal tumour <sup>4</sup>. However it can mimic more sinister types of breast cancer on both imaging and clinical findings <sup>8</sup>.</p><h4>Epidemiology</h4><p>They account for only 0.2% of all breast tumours <sup>9</sup>.</p><h4>Clinical presentation</h4><p>A desmoid tumour appears as a solitary, hard and painless nodule, which sometimes can be attached to the skin or to the pectoral muscle fascia.</p><h4>Pathology</h4><p>The entity is pathologically indistinguishable from <a href="/articles/fibromatosis">fibromatosis </a>occurring elsewhere in the body. The tumour has a with a fibroblastic and myofibroblastic origin.</p><h5>Associations</h5><p>Recognised associations include:</p><ul>
- +<li>
- +<a href="/articles/gardner-syndrome">Gardner syndrome</a> <sup>4,9</sup>
- +</li>
- +<li>saline or silicone <a href="/articles/breast-implants">breast implants</a><sup><a href="/articles/breast-implants"> </a>4,9</sup>
- +</li>
- +<li>prior surgical trauma <sup>4,9</sup>
- +</li>
- +</ul><h5>Location</h5><ul><li>while it can occur anywhere in the breast, lesions may tend to occur in close proximity to pectoral muscles</li></ul><h4>Radiographic features</h4><h5>Mammography</h5><p>A spicutated irregular non calcified mass is considered the most common mammographic finding.</p><h5>Breast ultrasound</h5><p>Fibromatosis typically appears as a solid, spiculated or microlobulated, irregular hypo-echoic mass with straightening and tethering of Cooper ligaments, which is very difficult to differentiate from a malignant lesion </p><h5>Breast MRI</h5><p>Usually seen an irregular breast mass</p><ul>
- +<li>
- +<strong>T1: </strong>mammary fibromatosi may appear as ill-defined, hypo- to isointense masses</li>
- +<li>
- +<strong>T2:</strong> usually heterogeneously hyper-intense in signal</li>
- +<li>
- +<strong>T1 C+ (Gd):</strong> often show suspicious, slow enhancement after contrast administration </li>
- +</ul><p>MRI is often useful to show chest wall involvement in selected cases prior to surgical planning.</p><h4>Treatment and prognosis</h4><p>Although it is a benign non metastasing tumour, it can be locally aggessive. Wide local excision with clear margins remains the treatment of choice <sup>5</sup>. Recurrence rates can be high, especially in those with positive margins. Recurrence is less likely if a wide excision is performed and resection margins are made sure to be disease-free. Recurrences are also often treated with radical excision, as the primary tumour.</p><h4>See also</h4><ul>
- +<li><a href="/articles/desmoid-tumour">desmoid tumour</a></li>
- +<li><a href="/articles/fibrosarcoma-of-the-breast">fibrosarcoma of the breast</a></li>
- +</ul>
References changed:
- 12. Ellen Shaw De Paredes. Atlas of Mammography. (2007) ISBN: 9780781764339 - <a href="http://books.google.com/books?vid=ISBN9780781764339">Google Books</a>
- 12. Eurorad teaching files : <a href="http://www.eurorad.org/eurorad/case.php?id=9181&lang=en"> Case 9181
- 13. Paredes ES. Atlas of mammography. Lippincott Williams & Wilkins. (2007) ISBN:0781764335. <a href="http://books.google.com/books?vid=ISBN0781764335">Read it at Google Books</a> - <a href="http://www.amazon.com/gp/product/0781764335?ie=UTF8&tag=radiopaediaor-20&linkCode=as2&camp=1789&creative=9325&creativeASIN=0781764335">Find it at Amazon</a><div class="ref_v2"></div>
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