Gadobutrol

Changed by Tom Foster, 26 Nov 2020

Updates to Article Attributes

Body was changed:

Gadobutrol (also known as Gadovist/GadavistTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging.

  • cyclic, non-ionic molecule 
  • 100% renally excreted
  • T1 relaxivity @ 1.5 T: 4.9-5.5 (slightly higher than other extracellular contrast agents)
  • concentration: 1.0 mmol/ml/mL
  • recommended dosage: 0.1 mmol/kg

Of note, gadobutrol's standard concentration (1 mmol/ml/mL) is is 2x - 4x than that of other commercially-available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in post-contrast dynamic sequences.

Indications

As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.

  • -<li>concentration: 1.0 mmol/ml</li>
  • +<li>concentration: 1.0 mmol/mL</li>
  • -</ul><p>Of note, gadobutrol's standard concentration (1 mmol/ml) is 2x - 4x than that of other commercially-available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in post-contrast dynamic sequences.</p><h5>Indications</h5><p>As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.</p>
  • +</ul><p>Of note, gadobutrol's standard concentration (1 mmol/mL) is 2x - 4x than that of other commercially-available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in post-contrast dynamic sequences.</p><h5>Indications</h5><p>As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.</p>

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