Gadobutrol
Updates to Article Attributes
Gadobutrol (also known as Gadovist/GadavistTM
cyclic, non-ionic molecule
100% renally excreted
T1 relaxivity
@at 1.5 T: 4.9-5.5 (slightly higher than other extracellular contrast agents)concentration: 1.0 mmol/mL
recommended dosage: 0.1 mmol/kg
Of note, gadobutrol's standard concentration (1 mmol/mL) is 2x - 4x2-4 times greater than that of other commercially-available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in post-contrast dynamic sequences.
Indications
As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.
-<p><strong>Gadobutrol </strong>(also known as <strong>Gadovist/Gadavist<sup>TM</sup></strong>) is an extracellular intravenous <a href="/articles/mri-contrast-agents">contrast agent</a> used in magnetic resonance imaging.</p><ul>-<li>cyclic, non-ionic molecule </li>-<li>100% renally excreted</li>-<li>T1 relaxivity @ 1.5 T: 4.9-5.5 (slightly higher than other extracellular contrast agents)</li>-<li>concentration: 1.0 mmol/mL</li>-<li>recommended dosage: 0.1 mmol/kg</li>-</ul><p>Of note, gadobutrol's standard concentration (1 mmol/mL) is 2x - 4x than that of other commercially-available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in post-contrast dynamic sequences.</p><h5>Indications</h5><p>As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.</p>- +<p><strong>Gadobutrol </strong>(also known as <strong>Gadovist/Gadavist</strong>) is an extracellular intravenous <a href="/articles/mri-contrast-agents">contrast agent</a> used in magnetic resonance imaging.</p><ul>
- +<li><p>cyclic, non-ionic molecule </p></li>
- +<li><p>100% renally excreted</p></li>
- +<li><p>T1 relaxivity at 1.5 T: 4.9-5.5 (slightly higher than other extracellular contrast agents)</p></li>
- +<li><p>concentration: 1.0 mmol/mL</p></li>
- +<li><p>recommended dosage: 0.1 mmol/kg</p></li>
- +</ul><p>Of note, gadobutrol's standard concentration (1 mmol/mL) is 2-4 times greater than that of other commercially-available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in post-contrast dynamic sequences.</p><h5>Indications</h5><p>As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.</p>
References changed:
- 1. Guglielmo F, Mitchell D, Gupta S. Gadolinium Contrast Agent Selection and Optimal Use for Body MR Imaging. Radiol Clin North Am. 2014;52(4):637-56. <a href="https://doi.org/10.1016/j.rcl.2014.02.004">doi:10.1016/j.rcl.2014.02.004</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/24889165">Pubmed</a>
- 1. Guglielmo FF, Mitchell DG, Gupta S. Gadolinium contrast agent selection and optimal use for body MR imaging. Radiol. Clin. North Am. 2014;52 (4): 637-56. <a href="http://dx.doi.org/10.1016/j.rcl.2014.02.004">doi:10.1016/j.rcl.2014.02.004</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/24889165">Pubmed citation</a><span class="auto"></span>
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