Glenn shunt
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Article Attributes
The Glenn shunt, also known as Glenn procedure,is a palliative procedure for a variety of cyanotic congenital heart disease.
Rationale
In this procedure, the systemic venous return is re-directed to the pulmonary circulation, bypassing the right heart 1-3.
It can be used in a variety of situations, including:
- cyanotic congenital cardiac anomalies that eventually lead to a single anatomical or functional ventricle (i.e. tricuspid atresia)
- right or left ventricular hypoplasia (i.e. hypoplastic left heart syndrome)
- as an initial step before the Fontan form of a total right heart bypass
Procedure
The classic (unidirectional) Glenn shunt involved:
- ligation of the distal end of the superior vena cava (SVC)
- anastomosis of the side of the SVC above the ligation with the distal end of the divided right pulmonary artery, providing unilateral (right) lung perfusion
In a modified (bidirectional) Glenn or hemi-Fontan shunt, anastomosis is created between the transected end of the SVC and the side of the undivided right pulmonary artery, providing balanced bilateral pulmonary circulation 1-3.
The Glenn shunt is now considered the first stage of a complete systemic venous to pulmonary arterial anastomosis, also known as a Fontan procedure. The Fontan procedure is basically a bidirectional Glenn shunt combined with a conduit or tunnel through or around the right atrium, shunting blood from the inferior vena cava to the pulmonary arteries.
Complications
Complications of the Glenn shunt include 2-4:
-
superior vena cava (SVC)SVC syndrome - shunt and pulmonary artery thrombosis
- stenosis of the cavopulmonary anastomosis
- sinus node injury with subsequent rhythm disturbance
- pulmonary arteriovenous malformation (AVM)
- aortopulmonary collaterals
History and etymology
The Glenn shunt was introduced in 1958 by Dr. William Glenn and modifications to the procedure were published by Dr. Gaetano Azzolina in 1973 5-6.
-<li>cyanotic <a title="Congenital cardiac anomalies" href="/articles/congenital-cardiovascular-anomalies">congenital cardiac anomalies</a> that eventually lead to a single anatomical or functional ventricle (i.e. <a title="Tricuspid atresia" href="/articles/tricuspid-atresia">tricuspid atresia</a>)</li>-<li>right or left ventricular hypoplasia (i.e. <a title="Hypoplastic left heart syndrome" href="/articles/hypoplastic-left-heart-syndrome">hypoplastic left heart syndrome</a>)</li>- +<li>cyanotic <a href="/articles/congenital-cardiovascular-anomalies">congenital cardiac anomalies</a> that eventually lead to a single anatomical or functional ventricle (i.e. <a href="/articles/tricuspid-atresia">tricuspid atresia</a>)</li>
- +<li>right or left ventricular hypoplasia (i.e. <a href="/articles/hypoplastic-left-heart-syndrome">hypoplastic left heart syndrome</a>)</li>
-<li>ligation of the distal end of the superior vena cava (SVC)</li>- +<li>ligation of the distal end of the <a href="/articles/superior-vena-cava">superior vena cava</a> (SVC)</li>
-</ul><p>In a modified (bidirectional) Glenn or hemi-Fontan shunt, anastomosis is created between the transected end of the SVC and the side of the undivided right pulmonary artery, providing balanced bilateral pulmonary circulation <sup>1-3</sup>. </p><p>The Glenn shunt is now considered the first stage of a complete systemic venous to pulmonary arterial anastomosis, also known as a <a href="/articles/fontan-procedure">Fontan procedure</a>. The Fontan procedure is basically a bidirectional Glenn shunt combined with conduit or tunnel through or around right atrium, shunting blood from the inferior vena cava to the pulmonary arteries.</p><p><strong style="font-size:1.5em; font-weight:bold">Complications</strong></p><p>Complications of the Glenn shunt include <sup>2-4</sup>:</p><ul>-<li>superior vena cava (SVC) syndrome</li>- +</ul><p>In a modified (bidirectional) Glenn or hemi-Fontan shunt, anastomosis is created between the transected end of the SVC and the side of the undivided right pulmonary artery, providing balanced bilateral pulmonary circulation <sup>1-3</sup>. </p><p>The Glenn shunt is now considered the first stage of a complete systemic venous to pulmonary arterial anastomosis, also known as a <a href="/articles/fontan-procedure">Fontan procedure</a>. The Fontan procedure is basically a bidirectional Glenn shunt combined with a conduit or tunnel through or around the <a href="/articles/right-atrium">right atrium</a>, shunting blood from the <a href="/articles/inferior-vena-cava-1">inferior vena cava</a> to the pulmonary arteries.</p><h4>Complications</h4><p>Complications of the Glenn shunt include <sup>2-4</sup>:</p><ul>
- +<li><a href="/articles/superior-vena-cava-obstruction">SVC syndrome</a></li>
-<li>pulmonary arteriovenous malformation (AVM)</li>- +<li><a href="/articles/pulmonary-arteriovenous-malformation">pulmonary arteriovenous malformation (AVM)</a></li>
References changed:
- 2. Tomasian A, Malik S, Shamsa K, Krishnam M. Congenital Heart Diseases: Post-Operative Appearance on Multi-Detector CT-A Pictorial Essay. Eur Radiol. 2009;19(12):2941-9. <a href="https://doi.org/10.1007/s00330-009-1474-7">doi:10.1007/s00330-009-1474-7</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/19513718">Pubmed</a>
- 3. Fredenburg T, Johnson T, Cohen M. The Fontan Procedure: Anatomy, Complications, and Manifestations of Failure. Radiographics. 2011;31(2):453-63. <a href="https://doi.org/10.1148/rg.312105027">doi:10.1148/rg.312105027</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/21415190">Pubmed</a>
- 4. Pike N, Vricella L, Feinstein J, Black M, Reitz B. Regression of Severe Pulmonary Arteriovenous Malformations After Fontan Revision and "Hepatic Factor" Rerouting. Ann Thorac Surg. 2004;78(2):697-9. <a href="https://doi.org/10.1016/j.athoracsur.2004.02.003">doi:10.1016/j.athoracsur.2004.02.003</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/15276554">Pubmed</a>
- 5. Glenn W. Circulatory Bypass of the Right Side of the Heart. IV. Shunt Between Superior Vena Cava and Distal Right Pulmonary Artery; Report of Clinical Application. N Engl J Med. 1958;259(3):117-20. <a href="https://doi.org/10.1056/NEJM195807172590304">doi:10.1056/NEJM195807172590304</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/13566431">Pubmed</a>
- 6. Azzolina G, Eufrate S, Pensa P. Tricuspid Atresia: Experience in Surgical Management with a Modified Cavopulmonary Anastomosis. Thorax. 1972;27(1):111-5. <a href="https://doi.org/10.1136/thx.27.1.111">doi:10.1136/thx.27.1.111</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/5017561">Pubmed</a>
- 1. Gaca A, Jaggers J, Dudley L, Bisset G. Repair of Congenital Heart Disease: A Primer-Part 1. Radiology. 2008;247(3):617-31. <a href="https://doi.org/10.1148/radiol.2473061909">doi:10.1148/radiol.2473061909</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/18375837">Pubmed</a>
Tags changed:
- congenital cardiac anomalies
- cardiac
- cases
Systems changed:
- Cardiac
- Vascular