Question 481
{"accessible":false,"alternatives":[{"id":2417,"text":"WHO grade II diffuse astroctyoma"},{"id":2418,"text":"WHO grade II oligodendroglioma"},{"id":2419,"text":"WHO grade III anaplastic astrocytoma"},{"id":2420,"text":"WHO grade III anaplastic oligodendroglioma"},{"id":2421,"text":"WHO grade IV glioblastoma"}],"archived":false,"correctAlternativeId":2419,"explanation":"\u003cp\u003eGliomatosis cerebri has had a number of changes to its definition over the years. In earlier classifications, it was considered a distinct entity. In the 2016 edition of the WHO classification of CNS tumors, it was demoted to a 'growth pattern' and most commonly seen in IDH wild-type anaplastic astrocytomas.\u0026nbsp;\u003c/p\u003e\u003cp\u003eNow, in the 2021 edition, the vast majority of IDH-wildtype astrocytic tumors will qualify as glioblastomas either on the basis of histology alone or due to the presence of a variety of molecular markers.\u0026nbsp;\u003c/p\u003e\u003cp\u003eThus presently, gliomatosis cerebri is most commonly encountered in glioblastomas.\u0026nbsp;\u003c/p\u003e","id":481,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/819","nextQuestionPath":"/articles/gliomatosis-cerebri/questions/480","relatedArticles":[],"alsoUsedIn":[],"stem":"\u003cp\u003eIn the 2016 (revised 4th edition) of the WHO classification of CNS tumors, gliomatosis cerebri\u0026nbsp;growth pattern was\u0026nbsp;most considered to most commonly occur in...\u0026nbsp;\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/481"}],"attemptsPercentages":[{"alternativeId":"2420","percentage":6},{"alternativeId":"2419","percentage":39},{"alternativeId":"2417","percentage":22},{"alternativeId":"2418","percentage":5},{"alternativeId":"2421","percentage":28}],"promptToLogin":false,"questionManager":false,"articleId":"gliomatosis-cerebri"}