Question 973
{"accessible":false,"alternatives":[{"id":4877,"text":"biliary atresia"},{"id":4878,"text":"Crigler-Najjar syndrome"},{"id":4879,"text":"glucose-6-phosphate dehydrogenase (G6PD) deficiency"},{"id":4880,"text":"Lucey-Driscoll syndrome"},{"id":4881,"text":"sepsis"}],"archived":false,"correctAlternativeId":4877,"explanation":"\u003cp\u003e\u003ca title=\"Kernicterus\" class=\"internal\" href=\"/articles/kernicterus\"\u003eKernicterus\u003c/a\u003e\u0026nbsp;describes the chronic, toxic, permanent sequelae of high levels of unconjugated bilirubin on the central nervous system of infants. In these infants, unconjugated bilirubin deposits in the\u0026nbsp;\u003ca href=\"https://radiopaedia.org/articles/globus-pallidus\"\u003eglobus pallidi\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://radiopaedia.org/articles/subthalamic-nuclei\"\u003esubthalamic nuclei\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://radiopaedia.org/articles/hippocampus\"\u003ehippocampus\u003c/a\u003e\u0026nbsp;(especially CA2-CA3),\u0026nbsp;\u003ca href=\"https://radiopaedia.org/articles/putamen\"\u003eputamen\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://radiopaedia.org/articles/thalamus\"\u003ethalamus\u003c/a\u003e, and cranial nerve nuclei (especially of CN III, IV, and VI). On MRI, these regions, especially the posteromedial borders of the putamen,\u0026nbsp;demonstrate high T1 and T2 signal.\u003c/p\u003e\u003cp\u003eOf the options available, only \u003ca title=\"Biliary atresia\" class=\"internal\" href=\"/articles/biliary-atresia\"\u003ebiliary atresia\u003c/a\u003e is a cause\u0026nbsp;of neonatal conjugated jaundice instead of unconjugated jaundice.\u003c/p\u003e","id":973,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/973","nextQuestionPath":null,"relatedArticles":[{"id":5176,"title":"Biliary atresia","link":"/articles/biliary-atresia?lang=us"},{"id":26998,"title":"Jaundice","link":"/articles/jaundice?lang=us"},{"id":56992,"title":"Kernicterus","link":"/articles/kernicterus?lang=us"}],"alsoUsedIn":[],"stem":"\u003cp\u003eWhich of the following is\u0026nbsp;\u003cstrong\u003eNOT\u003c/strong\u003e\u0026nbsp;an underlying etiology of kernicterus?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/973"}],"attemptsPercentages":[{"alternativeId":"4878","percentage":9},{"alternativeId":"4880","percentage":29},{"alternativeId":"4881","percentage":15},{"alternativeId":"4877","percentage":32},{"alternativeId":"4879","percentage":15}],"promptToLogin":false,"questionManager":false,"articleId":"hemolytic-anemia"}