Halo sign (chest)

Changed by Bruno Di Muzio, 8 Apr 2019

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The halo sign in chest imaging is a feature seen on lung window settings (typically HRCT), ground glass opacity surrounding a pulmonary nodule or mass and represents haemorrhage. It is typically seen in angioinvasive aspergillosis.

Pathology

Histopathologically, it represents a focus of pulmonary infarction surrounded by alveolar haemorrhage.

Diagnostic considerations

Other entities that may give a halo sign include:

-<p>The <strong>halo sign</strong> in chest imaging is a feature seen on lung window settings (typically <a title="HRCT lung" href="/articles/high-resolution-ct">HRCT</a>), <a href="/articles/ground-glass-opacification-3">ground glass opacity</a> surrounding a pulmonary nodule or mass and represents haemorrhage. It is typically seen in <a href="/articles/angioinvasive-aspergillosis">angioinvasive aspergillosis</a>.</p><h4>Pathology</h4><p>Histopathologically, it represents a focus of pulmonary infarction surrounded by alveolar haemorrhage.</p><h4>Diagnostic considerations</h4><p>Other entities that may give a halo sign include:</p><h5>Infectious disease</h5><ul>
+<p>The <strong>halo sign</strong> in chest imaging is a feature seen on lung window settings (typically <a href="/articles/high-resolution-ct">HRCT</a>), <a href="/articles/ground-glass-opacification-3">ground glass opacity</a> surrounding a pulmonary nodule or mass and represents haemorrhage. It is typically seen in <a href="/articles/angioinvasive-aspergillosis">angioinvasive aspergillosis</a>.</p><h4>Pathology</h4><p>Histopathologically, it represents a focus of pulmonary infarction surrounded by alveolar haemorrhage.</p><h4>Diagnostic considerations</h4><p>Other entities that may give a halo sign include:</p><h5>Infectious disease</h5><ul>
~~-<li><a href="/articles/pulmonary-coccidioidomycosis">pulmonary coccidoidomycosis</a></li>~~
+<li><a href="/articles/pulmonary-coccidioidomycosis">pulmonary coccidioidomycosis</a></li>
-<a href="/articles/adenocarcinoma-of-the-lung">adenocarcinoma of lung</a>, <a href="/articles/adenocarcinoma-in-situ-of-the-lung">adenocarcinoma in situ</a> or minimally invasive (formerly <a href="/articles/adenocarcinoma-in-situ-minimally-invasive-adenocarcinoma-and-invasive-adenocarcinoma-of-lung">bronchioalveolar carcinoma</a>) - has been described as the most commonly encountered with HS in immunocompetent patients <sup>5</sup>
+<a href="/articles/adenocarcinoma-of-the-lung">adenocarcinoma of the lung</a>, <a href="/articles/adenocarcinoma-in-situ-of-the-lung">adenocarcinoma in situ</a> or minimally invasive (formerly <a href="/articles/adenocarcinoma-in-situ-minimally-invasive-adenocarcinoma-and-invasive-adenocarcinoma-of-lung">bronchioalveolar carcinoma</a>) - has been described as the most commonly encountered with HS in immunocompetent patients <sup>5</sup>
~~-<li><a href="/articles/squamous-cell-carcinoma-of-the-lung">squamous cell carcinoma of lung</a></li>~~
+<li><a href="/articles/squamous-cell-carcinoma-of-the-lung">squamous cell carcinoma of the lung</a></li>
~~-<li>iatrogenic injury</li>~~
+<li>iatrogenic injury<ul><li>
+<a title="Radiation pneumonitis" href="/articles/radiation-pneumonitis">radiation pneumonitis</a> <sup>6</sup>
+</li></ul>
+</li>

References changed:

6. Benveniste M, Gomez D, Carter B et al. Recognizing Radiation Therapy-Related Complications in the Chest. Radiographics. 2019;39(2):344-66. <a href="https://doi.org/10.1148/rg.2019180061">doi:10.1148/rg.2019180061</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/30844346">Pubmed</a>

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