Hemivertebra
Updates to Article Attributes
Hemivertebra is a type of vertebral anomaly and results from a lack of formation of one half of a vertebral body. It can be a common cause of a congenital scoliosis.
Epidemiology
The estimated incidence is at ~0.3 per 1000 live births 2.
Pathology
It falls under the spectrum of segmentational anomalies and can involve one or multiple levels.
A hemivertebra acts as a wedge within the vertebral column, resulting in curvature away from the side on which it is present.
Associations
Recognised associations are many and include:
- Aicardi syndrome
- cleidocranial dysostosis
- gastroschisis 3
- Gorlin syndrome
- fetal pyelectasis 3
- Jarcho-Levin syndrome
- OEIS complex
- VACTERL association
- mucopolysaccharidosis 9
This list supposed to be a lot longer than this. If you know more, do add in with a relevant journal reference.
Classification
A hemivertebra can be classified according to many types which include:
Attachment
- fully segmental (free)
- not attached to either vertebra above or below
- most concerning
- semi segmental: half segment is fused with vertebra above or below with no intervening intervertebral disc
- non segemental
- not separated from (i.e. connected to) either level above or below
- causes less of a concern
- incarcerated
- joined by pedicles to levels above and below
- causes less of a concern
Orientation
- dorsal hemivertebra: classically results in kyphosis
- lateral hemivertebra: classically results in scoliosis
- ventral hemivertebra (extremely rare): results in lordosis
Radiographic features
Antenatal ultrasound
A hemivertebra may be seen as an asymmetrical vertebral body on sagittal or coronal scanning, while on axial scanning, a focal defect may be seen on either side of the vertebral column 5.
Plain radiograph / CT
Usually directly outlines the bony anomaly and is often seen as a wedge shaped-shaped vertebral body.
Treatment and prognosis
The prognosis can be variable dependant on the type of segmentation anomaly, from being a progressive to a non progressive deformity. The strongest negative impact is when a hemivertebra occurs at the lumbo-sacral level 7.
Differential diagnosis
-<p><strong>Hemivertebra</strong> is a type of <a href="/articles/vertebral-anomalies">vertebral anomaly</a> and results from a lack of formation of one half of a vertebral body. It can be a common cause of a congenital <a title="Scoliosis" href="/articles/scoliosis">scoliosis</a>. </p><h4>Epidemiology</h4><p>The estimated incidence is at ~0.3 per 1000 live births <sup>2</sup>.</p><h4>Pathology</h4><p>It falls under the spectrum of segmentational anomalies and can involve one or multiple levels.</p><p>A hemivertebra acts as a wedge within the vertebral column, resulting in curvature away from the side on which it is present. </p><h5>Associations</h5><p>Recognised associations are many and include:</p><ul>- +<p><strong>Hemivertebra</strong> is a type of <a href="/articles/vertebral-anomalies">vertebral anomaly</a> and results from a lack of formation of one half of a vertebral body. It can be a common cause of a congenital <a href="/articles/scoliosis">scoliosis</a>. </p><h4>Epidemiology</h4><p>The estimated incidence is at ~0.3 per 1000 live births <sup>2</sup>.</p><h4>Pathology</h4><p>It falls under the spectrum of segmentational anomalies and can involve one or multiple levels.</p><p>A hemivertebra acts as a wedge within the vertebral column, resulting in curvature away from the side on which it is present. </p><h5>Associations</h5><p>Recognised associations are many and include:</p><ul>
-</ul><p><em>This list supposed to be lot longer than this. If you know more, do add in with a relevant journal reference.</em></p><h5>Classification</h5><p>A hemivertebra can be classified according to many types which include:</p><h6>Attachment</h6><ul>- +</ul><p><em>This list supposed to be a lot longer than this. If you know more, do add in with a relevant journal reference.</em></p><h5>Classification</h5><p>A hemivertebra can be classified according to many types which include:</p><h6>Attachment</h6><ul>
-<a href="/articles/dorsal-hemivertebra">dorsal hemivertebra</a>: classically results in a <a title="Kyphosis" href="/articles/kyphosis">kyphosis</a>- +<a href="/articles/dorsal-hemivertebra">dorsal hemivertebra</a>: classically results in <a href="/articles/kyphosis">kyphosis</a>
-<a href="/articles/lateral-hemivertebra">lateral hemivertebra</a>: classically results in a <a title="Scoliosis" href="/articles/scoliosis">scoliosis</a>- +<a href="/articles/lateral-hemivertebra">lateral hemivertebra</a>: classically results in <a href="/articles/scoliosis">scoliosis</a>
-<a href="/articles/ventral-hemivertebra">ventral hemivertebra</a> (extremely rare): results in a <a title="lordosis" href="/articles/lordosis">lordosis</a>- +<a href="/articles/ventral-hemivertebra">ventral hemivertebra</a> (extremely rare): results in <a href="/articles/lordosis">lordosis</a>
-</ul><h4>Radiographic features</h4><h5>Antenatal ultrasound</h5><p>A hemivertebra may be seen as an asymmetrical vertebral body on sagittal or coronal scanning, while on axial scanning, a focal defect may be seen on either side of the vertebral column <sup>5</sup>.</p><h5>Plain radiograph / CT</h5><p>Usually directly outlines the bony anomaly and is often seen as a wedge shaped vertebral body.</p><h4>Treatment and prognosis</h4><p>The prognosis can be variable dependant on the type of segmentation anomaly, from being a progressive to a non progressive deformity. The strongest negative impact is when a hemivertebra occurs at the lumbo-sacral level <sup>7</sup>.</p><h4>Differential diagnosis</h4><ul>-<li><a title="Block vertebrae" href="/articles/block-vertebra">block vertebrae</a></li>-<li><a title="Bullet shaped vertebra" href="/articles/bullet-shaped-vertebra">bullet shaped vertebrae</a></li>-<li><a title="Butterfly vertebrae" href="/articles/butterfly-vertebra">butterfly vertebrae</a></li>- +</ul><h4>Radiographic features</h4><h5>Antenatal ultrasound</h5><p>A hemivertebra may be seen as an asymmetrical vertebral body on sagittal or coronal scanning, while on axial scanning, a focal defect may be seen on either side of the vertebral column <sup>5</sup>.</p><h5>Plain radiograph / CT</h5><p>Usually directly outlines the bony anomaly and is often seen as a wedge-shaped vertebral body.</p><h4>Treatment and prognosis</h4><p>The prognosis can be variable dependant on the type of segmentation anomaly, from being a progressive to a non progressive deformity. The strongest negative impact is when a hemivertebra occurs at the lumbo-sacral level <sup>7</sup>.</p><h4>Differential diagnosis</h4><ul>
- +<li><a href="/articles/block-vertebra">block vertebrae</a></li>
- +<li><a href="/articles/bullet-shaped-vertebra">bullet shaped vertebrae</a></li>
- +<li><a href="/articles/butterfly-vertebra">butterfly vertebrae</a></li>