Hepatic stellate cells

Last revised by Rohit Sharma on 20 Feb 2024

Citation, DOI, disclosures and article data

Citation:

Nicoletti D, Sharma R, Knipe H, Hepatic stellate cells. Reference article, Radiopaedia.org (Accessed on 29 Apr 2024) https://doi.org/10.53347/rID-177075

DOI:

https://doi.org/10.53347/rID-177075

Permalink:

https://radiopaedia.org/articles/177075

rID:

177075

Article created:

19 Oct 2023, Domenico Nicoletti ◉

Disclosures:

At the time the article was created Domenico Nicoletti had no financial relationships to ineligible companies to disclose.

View Domenico Nicoletti's current disclosures

Last revised:

20 Feb 2024, Rohit Sharma ◉

Disclosures:

At the time the article was last revised Rohit Sharma had no financial relationships to ineligible companies to disclose.

View Rohit Sharma's current disclosures

Revisions:

3 times, by 3 contributors - see full revision history and disclosures

Systems:

Hepatobiliary

Sections:

Anatomy

Tags:

refs, stub, re-write

Hepatic stellate cells present in the perisinusoidal space of Disse between the fenestrated sinusoidal endothelial cell layer and hepatic epithelial cells, store vitamin A. They participate in liver development and regeneration if activated by damage such as after chronic hepatitis by producing excessive extracellular matrix and activating angiogenesis in the liver fibrogenesis. Furthermore HSCs are a significant component of the tumor microenvironment of hepatocellular carcinoma.