Iofendylate
Updates to Article Attributes
Iophendylate (generic name is iodophenylundecylic acid)and sold under the tradename Myodil (except the USA where it was marketed as Pantopaque) was an oil-based contrast medium that was previously used for myelography. It was first used in 1944, but officially discontinued in 1988 6.
The iodine moiety of the compound causes high attenuation on radiography and CT 6. Its major drawback was its extremely slow resorption, with contrast medium persisting in situ for decades 6. Complete removal through aspiration was usually impossible after a procedure, and the remaining droplets could lead to chronic irritation and severe arachnoiditis.
-<p><strong>Iophendylate</strong> (generic name is <strong>iodophenylundecylic acid</strong>)<strong> </strong>and sold under the tradename <strong>Myodil</strong> (except the USA where it was marketed as <strong>Pantopaque</strong>) was an oil-based contrast medium that was previously used for <a href="/articles/myelography">myelography</a>. It was first used in 1944, but officially discontinued in 1988 <sup>6</sup>.</p><p>The <a title="Iodine" href="/articles/iodine">iodine</a> moiety of the compound causes high attenuation on radiography and CT <sup>6</sup>. Its major drawback was its extremely slow resorption, with contrast medium persisting in situ for decades <sup>6</sup>. Complete removal through aspiration was usually impossible after a procedure, and the remaining droplets could lead to chronic irritation and severe <a href="/articles/arachnoiditis">arachnoiditis</a>.</p>- +<p><strong>Iophendylate</strong> (generic name is <strong>iodophenylundecylic acid</strong>)<strong> </strong>and sold under the tradename <strong>Myodil</strong> (except the USA where it was marketed as <strong>Pantopaque</strong>) was an oil-based contrast medium that was previously used for <a href="/articles/myelography">myelography</a>. It was first used in 1944, but officially discontinued in 1988 <sup>6</sup>.</p><p>The <a href="/articles/iodine">iodine</a> moiety of the compound causes high attenuation on radiography and CT <sup>6</sup>. Its major drawback was its extremely slow resorption, with contrast medium persisting in situ for decades <sup>6</sup>. Complete removal through aspiration was usually impossible after a procedure, and the remaining droplets could lead to chronic irritation and severe <a href="/articles/arachnoiditis">arachnoiditis</a>.</p>