Question 343
{"accessible":false,"alternatives":[{"id":1688,"text":"prolonged mean transit time (MTT)"},{"id":1690,"text":"prolonged time to maximum (Tmax)"},{"id":1689,"text":"prolonged time to peak (TTP)"},{"id":1691,"text":"reduced cerebral blood flow (CBF)"},{"id":1692,"text":"reduced cerebral blood volume (CBV)"},{"id":1693,"text":"reduced k-trans"}],"archived":false,"correctAlternativeId":1692,"explanation":"\u003cp\u003eThe infarct core is the part of the ischemic brain which has already infarcted or is destined to infarct regardless of therapy. It is defined as an area with prolonged MTT or Tmax (which are also prolonged in the \u003ca href=\"/articles/ischaemic-penumbra\"\u003epenumbra\u003c/a\u003e), and markedly decreased CBF and markedly reduced CBV.\u003c/p\u003e\u003cp\u003eNote, that if\u0026nbsp;one uses CBF to visually assess size of core, it is easy to overestimate infarct core, as the penumbra often has reduced CBF as well. So, even though some automated processes use\u0026nbsp;CBF to define the infarct core, CBV is a safer parameter if 'eye-balling' the scan.\u003c/p\u003e\u003cp\u003eCBV, on the other hand, is normal or slightly elevated in the penumbra.\u0026nbsp;\u003c/p\u003e","id":343,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/1768","nextQuestionPath":"/articles/ischaemic-penumbra/questions/252","relatedArticles":[{"id":24523,"title":"Infarct core","link":"/articles/infarct-core?lang=us"},{"id":24526,"title":"CT perfusion in ischemic stroke","link":"/articles/ct-perfusion-in-ischaemic-stroke?lang=us"}],"alsoUsedIn":[{"id":178,"kind":"Course","title":"Emergency Imaging in Stroke","link":"https://radiopaedia.org/courses/emergency-imaging-in-stroke"},{"id":908,"kind":"Course","title":"Neuroradiology Lectures - page 908","link":"https://radiopaedia.org/courses/neuroradiology-lectures/pages/908"},{"id":908,"kind":"Course","title":"2021 Virtual Conference Private Use - page 908","link":"https://radiopaedia.org/courses/2021-virtual-conference-private-use/pages/908"},{"id":908,"kind":"Course","title":"Radiopaedia 2021 - isoCME - page 908","link":"https://radiopaedia.org/courses/radiopaedia-2021-isocme/pages/908"},{"id":908,"kind":"Course","title":"New test course - page 908","link":"https://radiopaedia.org/courses/new-test-course/pages/908"},{"id":1192,"kind":"Course","title":"Neuroradiology Lectures - page 1192","link":"https://radiopaedia.org/courses/neuroradiology-lectures/pages/1192"},{"id":1192,"kind":"Course","title":"New test course - page 1192","link":"https://radiopaedia.org/courses/new-test-course/pages/1192"}],"stem":"\u003cp\u003eWhen visually assessing CT perfusion maps (without the aid of automated software)\u0026nbsp;ischemic infarct core is best delineated by which of the following parameters?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/343"}],"attemptsPercentages":[{"alternativeId":"1691","percentage":20},{"alternativeId":"1692","percentage":65},{"alternativeId":"1688","percentage":7},{"alternativeId":"1690","percentage":4},{"alternativeId":"1693","percentage":2},{"alternativeId":"1689","percentage":2}],"promptToLogin":false,"questionManager":false,"articleId":"ischemic-penumbra"}