Question 15
{"accessible":false,"alternatives":[{"id":69,"text":"1p19q co-deleted"},{"id":70,"text":"ATRX not mutated (intact)"},{"id":71,"text":"IDH-1 not mutated (wild-type) "},{"id":72,"text":"MGMT methylated (low activity)"},{"id":73,"text":"topoisomerase index = 5%"}],"archived":false,"correctAlternativeId":71,"explanation":"\u003cp\u003eIDH-1 wild-type, those that are not mutated, have a prognosis similar to glioblastoma, whereas all the other options are generally good prognostic factors.\u003c/p\u003e","id":15,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/2841","nextQuestionPath":null,"relatedArticles":[{"id":4910,"title":"Glioblastoma, IDH-wildtype","link":"/articles/glioblastoma-idh-wildtype?lang=us"},{"id":32837,"title":"Methylguanine-DNA methyltransferase (MGMT)","link":"/articles/methylguanine-dna-methyltransferase-mgmt?lang=us"},{"id":39164,"title":"1p19q codeletion","link":"/articles/1p19q-codeletion?lang=us"},{"id":41943,"title":"Alpha-thalassemia intellectual disability syndrome X-linked (ATRX) gene (tumor marker)","link":"/articles/alpha-thalassemia-intellectual-disability-syndrome-x-linked-atrx-gene-tumour-marker?lang=us"}],"alsoUsedIn":[],"stem":"\u003cp\u003eAll other things being equal, which of the following biomarkers confers the \u003cstrong\u003epoorest prognosis\u003c/strong\u003e in diffuse gliomas?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/15"}],"attemptsPercentages":[{"alternativeId":"70","percentage":4},{"alternativeId":"69","percentage":8},{"alternativeId":"73","percentage":3},{"alternativeId":"71","percentage":80},{"alternativeId":"72","percentage":5}],"promptToLogin":false,"questionManager":false,"articleId":"isocitrate-dehydrogenase-idh"}