Question 764
{"accessible":false,"alternatives":[{"id":3878,"text":"Herpes simplex virus (HSV)"},{"id":3879,"text":"Human immunodeficiency virus (HIV)"},{"id":3880,"text":"Human papilloma virus (HPV)"},{"id":3881,"text":"John Cunningham virus (JCV)"},{"id":3882,"text":"Varicella zoster virus (VZV)"}],"archived":false,"correctAlternativeId":3881,"explanation":"\u003cp\u003eProgressive multifocal leukoencephalopathy (PML) in the setting of multiple sclerosis is typically seen in patients treated with natalizumab with positive JC virus serology, representing latent infection of oligodendroglial cells.\u0026nbsp;\u003c/p\u003e","id":764,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/765","nextQuestionPath":null,"relatedArticles":[{"id":1700,"title":"Multiple sclerosis","link":"/articles/multiple-sclerosis?lang=us"},{"id":12098,"title":"Progressive multifocal leukoencephalopathy","link":"/articles/progressive-multifocal-leukoencephalopathy?lang=us"},{"id":11078,"title":"HIV/AIDS","link":"/articles/hivaids?lang=us"}],"alsoUsedIn":[],"stem":"\u003cp\u003eLatent infection with which virus is associated with the development of progressive multifocal leukoencephalopathy (PML) in individuals with multiple sclerosis?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/764"}],"attemptsPercentages":[{"alternativeId":"3878","percentage":5},{"alternativeId":"3882","percentage":4},{"alternativeId":"3880","percentage":1},{"alternativeId":"3879","percentage":9},{"alternativeId":"3881","percentage":81}],"promptToLogin":false,"questionManager":false,"articleId":"john-cunningham-virus"}