Question 904
{"accessible":false,"alternatives":[{"id":4546,"text":"long bones"},{"id":4547,"text":"mandible"},{"id":4548,"text":"ribs"},{"id":4549,"text":"skull"},{"id":4550,"text":"vertebrae"}],"archived":false,"correctAlternativeId":4549,"explanation":"\u003cp\u003e\u003ca href=\"https://radiopaedia.org/articles/langerhans-cell-histiocytosis\"\u003eLangerhans cell histiocytosis (LCH)\u003c/a\u003e\u0026nbsp;is a rare multisystem disease seen in young children characterized by clonal proliferation of Langerhans cells. The most commonly affected 'system' is the\u0026nbsp;\u003ca href=\"https://radiopaedia.org/articles/langerhans-cell-histiocytosis-skeletal-manifestations-1\"\u003eskeletal system\u003c/a\u003e, which is involved in nearly 80% of cases, and the most commonly affected bone or group of bones in children is the skull. In particular, the frontal bone is most involved in this demographic. All of the other alternatives in the question are also common sites of involvement in LCH. Notably, the mandible is the most commonly affected bone in adults with LCH.\u003c/p\u003e","id":904,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/1099","nextQuestionPath":"/articles/langerhans-cell-histiocytosis/questions/903","relatedArticles":[{"id":8478,"title":"Langerhans cell histiocytosis (skeletal manifestations)","link":"/articles/langerhans-cell-histiocytosis-skeletal-manifestations-1?lang=us"}],"alsoUsedIn":[],"stem":"\u003cp\u003eWhich\u0026nbsp;is the most commonly involved bone or group of bones in Langerhans cell histiocytosis in children?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/904"}],"attemptsPercentages":[{"alternativeId":"4546","percentage":16},{"alternativeId":"4548","percentage":2},{"alternativeId":"4547","percentage":2},{"alternativeId":"4550","percentage":5},{"alternativeId":"4549","percentage":76}],"promptToLogin":false,"questionManager":false,"articleId":"langerhans-cell-histiocytosis"}