Lung cancer (staging - IASLC 7th edition) (historical)
Updates to Article Attributes
Body
was changed:
Non-small cell lung cancer (NSCLC) staging can be accomplished both by the TNM system, or by the AJCC staging system.
For a general discussion of these tumours please refer to the article onnon-small cell lung cancer (NSCLC).
TNM system
The current 7th edition January 2010 NSCLC staging is as follows 4:
Primary tumour (T)
- Tx: malignant cells on cytology but no tumour found on bronchoscopy or imaging.
- Tis: carcinoma in situ
-
T1
- tumour size equal or less than
3cm3 cm - not involving the main bronchus
- T1a: smaller than 2 cm in longest dimension
-
T1b: larger than 2 cm but smaller
oror equal to 3 cm
- tumour size equal or less than
-
T2:
- tumour size more than 3cm but less/equal to 7cm or
- involving the main bronchus but >2 cm from carina
- visceral pleural
involvementinvolvement - lobar atelectasis extending to the hilum but not collapse of the entire lung
- T2a: larger than 3 cm but smaller than 5 cm
- T2b: larger than 5 cm but smaller than 7 cm
-
T3
- tumour size more than
77 cm or - tumour <
;2; 2 cm from carina but not involving trachea or carina - involvement of the chest wall, including Pancoast
tumourtumour, diaphragm, phrenic nerve, mediastinal pleura or parietal pericardium - separate tumour nodule(s) in the same lobe
- atelectasis or post obstructive pneumonitis of entire lung
- tumour size more than
-
T4
- any size tumour with:
- involvement of the trachea, oesophagus, recurrent laryngeal nerve vertebra, great vessels or heart
- separate tumour nodules in the same lung but not in the same lobe
Nodal status (N)
- Nx: regional nodes cannot be assessed
- N0: no regional nodal metastases
- N1: ipsilateral peribronchial, hilar or intrapulmonary nodes, including direct invasion
- N2: ipsilateral mediastinal or subcarinal nodes
- N3: contralateral nodal involvement ; ipsilateral or contralateral scalene or supraclavicular nodal involvement
Distant metastasis (M)
- Mx: distant metastases cannot be assessed
- M0: no distant metastases
-
M1: distant metastases present
- M1a: presence of a malignant pleural or pericardial effusion, pleural dissemination, or pericardial disease, and metastasis in opposite lung
- M1b: extrathoracic metastases
AJCC staging system
-
stage 0
- TNM equivalent: carcinoma in stiu
- resectable: yes
-
stage I
- TNM equivalent: T1 or T2, N0, M0
- resectable: yes
- 5 year survival: 47%
-
stage IIa
- TNM equivalent: T1, N1, M0
- resectable: yes
-
stage IIb
- TNM equivalent: T2, N1, M0 or T3, N0, M0
- resectable: yes
- 5 year survival: 26%
-
stage IIIa
- TNM equivalent: T1 or 2, N2, M0 or T3, N1 or 2, M0
- resectable: yes
--------------- accepted cut off between resectable and non resectable ----------
-
stage IIIb
- TNM equivalent: T1, 2 or 3, N3, M0 or T4, N0, 1, 2 or 3, M0
- resectable: no
- 5 year survival: 8%
-
stage IV
- TNM equivalent: any T, any N with M1
- resectable: no
- 5 year survival: 2%
Histological grade
- grade 1: well differentiated
- grade 2: moderately differentiated
- grade 3: poorly differentiated
- grade 4: undifferentiated
See also
-<p><strong>Non-small cell lung cancer (NSCLC) staging</strong> can be accomplished both by the <a href="/articles/tnm-staging-system">TNM system</a>, or by the AJCC staging system.</p><p>For a general discussion of these tumours please refer to the article on <a href="/articles/non-small-cell-lung-cancer">non-small cell lung cancer (NSCLC)</a>.</p><h5>TNM system</h5><p>The current <strong> 7<sup>th</sup> edition January 2010</strong> NSCLC staging is as follows <sup>4</sup>:</p><h6>Primary tumour (T)</h6><ul>- +<p><strong>Non-small cell lung cancer (NSCLC) staging</strong> can be accomplished both by the <a href="/articles/tnm-staging-system">TNM system</a>, or by the AJCC staging system.</p><p>For a general discussion of these tumours please refer to the article on <a href="/articles/non-small-cell-lung-cancer">non-small cell lung cancer (NSCLC)</a>.</p><h5>TNM system</h5><p>The current <strong> 7<sup>th</sup> edition January 2010</strong> NSCLC staging is as follows <sup>4</sup>:</p><h6>Primary tumour (T)</h6><ul>
-<li>tumour size equal or less than 3cm </li>- +<li>tumour size equal or less than 3 cm </li>
-<strong>T1b:</strong> larger than 2 cm but smaller or equal to 3 cm </li>- +<strong>T1b:</strong> larger than 2 cm but smaller or equal to 3 cm </li>
-<li>visceral pleural involvement</li>- +<li>visceral pleural involvement</li>
-<li>tumour size more than 7 cm or </li>-<li>-<strong> </strong>tumour <strong></strong><2 cm from carina but not involving trachea or carina</li>-<li>involvement of the chest wall, including Pancoast tumour, diaphragm, phrenic nerve, mediastinal pleura or parietal pericardium</li>- +<li>tumour size more than 7 cm or </li>
- +<li>tumour <strong></strong>< 2 cm from carina but not involving trachea or carina</li>
- +<li>involvement of the chest wall, including Pancoast tumour, diaphragm, phrenic nerve, mediastinal pleura or parietal pericardium</li>
-</ul>- +</ul><h4>See also </h4><ul><li><a title="Lung cancer staging IASCL 7th edition" href="/articles/lung-cancer-staging-iascl-7th-edition">lung cancer staging IASCL 7<sup>th</sup> edition</a></li></ul>