Question 1533
{"accessible":false,"alternatives":[{"id":7655,"text":"calcification"},{"id":7656,"text":"enlarged: over 20 mm"},{"id":7657,"text":"extranodal extension of tumor"},{"id":7658,"text":"rounded contour"}],"archived":false,"correctAlternativeId":7657,"explanation":"\u003cp\u003eWhile radiology is not particularly sensitive in detection of ENS, it is generally very specific. The other features do not have specificity for metastatic disease.\u003c/p\u003e\u003cp\u003eRef:\u0026nbsp;King AD, Tse GM, Yuen EH, To EW, Vlantis AC, Zee B, Chan AB, van Hasselt AC, Ahuja AT. Comparison of CT and MR imaging for the detection of extranodal neoplastic spread in metastatic neck nodes. (2004) European journal of radiology. 52 (3): 264-70. doi:10.1016/j.ejrad.2004.03.004 - https://www.ncbi.nlm.nih.gov/pubmed/15544904\u003c/p\u003e","id":1533,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/2374","nextQuestionPath":null,"relatedArticles":[],"alsoUsedIn":[{"id":237,"kind":"Course","title":"Head \u0026 Neck Imaging Pearls","link":"https://radiopaedia.org/courses/head-neck-imaging-pearls"},{"id":587,"kind":"Course","title":"Radiology lectures for ENT Trainees - page 587","link":"https://radiopaedia.org/courses/radiology-lectures-for-ent-trainees/pages/587"},{"id":587,"kind":"Course","title":"Radiopaedia 2020 - Lectures Only - page 587","link":"https://radiopaedia.org/courses/radiopaedia-2020-exclusive/pages/587"},{"id":587,"kind":"Course","title":"Head \u0026 Neck Lectures - page 587","link":"https://radiopaedia.org/courses/head-neck-lectures/pages/587"},{"id":587,"kind":"Course","title":"2020 Virtual Conference Private Use - page 587","link":"https://radiopaedia.org/courses/2020-virtual-conference-private-use/pages/587"}],"stem":"\u003cp\u003eWhat is the most specific sign of malignant involvement of a node?\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/1533"}],"attemptsPercentages":[{"alternativeId":"7657","percentage":78},{"alternativeId":"7655","percentage":2},{"alternativeId":"7658","percentage":15},{"alternativeId":"7656","percentage":5}],"promptToLogin":false,"questionManager":false,"articleId":"lymph-node-enlargement"}