Multifocal glioblastoma
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Multifocal glioblastomas are tumours which have multiple discrete areas of contrast enhancing tumour embedded with, or connected by, T2/FLAIR signal abnormality. They are considered to be part of the one tumour.
Multifocal glioblastomas have been shown to have a poorer prognosis than solitary tumours2.
Differential diagnosis
This is in contrast tomulticentric glioblastomas, which have enhancing foci with normal intervening brain, and are thought to more likely represent synchronous but separate tumours.
-<p><strong>Multifocal glioblastomas</strong> are tumours which have multiple discrete areas of contrast enhancing tumour embedded with, or connected by, T2/FLAIR signal abnormality. They are considered to be part of the one tumour. </p><p>Multifocal glioblastomas have been shown to have a poorer prognosis than solitary tumours <sup>2</sup>. </p><h4>Differential diagnosis</h4><p>This is in contrast to <a href="/articles/multicentric-glioblastoma">multicentric glioblastomas</a>, which have enhancing foci with normal intervening brain, and are thought to more likely represent synchronous but separate tumours. </p>- +<p><strong>Multifocal glioblastomas</strong> are tumours which have multiple discrete areas of contrast enhancing tumour embedded with, or connected by, T2/FLAIR signal abnormality. They are considered to be part of the one tumour. </p><p>Multifocal glioblastomas have been shown to have a poorer prognosis than solitary tumours <sup>2</sup>. </p><h4>Differential diagnosis</h4><p>This is in contrast to <a href="/articles/multicentric-glioblastoma">multicentric glioblastomas</a>, which have enhancing foci with normal intervening brain, and are thought to more likely represent synchronous but separate tumours. </p>
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Image 6 MRI (T1 C+) ( create )
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