Question 328
{"accessible":false,"alternatives":[{"id":1601,"text":"appearing over an extended period of time"},{"id":1602,"text":"that have differing gradient echo characteristics"},{"id":1603,"text":"without central regions of necrosis"},{"id":1604,"text":"without connecting T2/FLAIR signal abnormality"},{"id":1605,"text":"which form a large conglomerate mass"}],"archived":false,"correctAlternativeId":1604,"explanation":"\u003cp\u003eMultifocal disease, which is found in ~20% of cases,\u0026nbsp;is that where multiple areas of enhancement are connected to each other by abnormal white matter signal, which represents microscopic spread to tumor cells.\u0026nbsp;Multicentric disease, on the other hand, is where no such connection can be seen.\u003c/p\u003e","id":328,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/596","nextQuestionPath":null,"relatedArticles":[{"id":4910,"title":"Glioblastoma, IDH-wildtype","link":"/articles/glioblastoma-idh-wildtype?lang=us"},{"id":38146,"title":"Multicentric glioblastoma","link":"/articles/multicentric-glioblastoma-1?lang=us"}],"alsoUsedIn":[],"stem":"\u003cp\u003eA multicentric glioblastoma (GBM) is one which has a number of discrete enhancing components...\u0026nbsp;\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/328"}],"attemptsPercentages":[{"alternativeId":"1604","percentage":58},{"alternativeId":"1602","percentage":8},{"alternativeId":"1603","percentage":5},{"alternativeId":"1601","percentage":8},{"alternativeId":"1605","percentage":20}],"promptToLogin":false,"questionManager":false,"articleId":"multifocal-glioblastoma"}