Muscle lymphoma

Changed by Henry Knipe, 3 Jan 2015

Updates to Article Attributes

Body was changed:

Muscle lymphoma is a rare manifestation of lymphoma

Epidemiology

Muscle lymphoma is rare, representing &gt<2% of all lymphomas. Average age of presentation is 70 years 1

Risk factors

Clinical presentation

Focal swelling and/or pain along with B-type symptoms 2. Any muscle can be involved but most commonly 1,2:

  • thigh
  • trunk
  • upper limb
  • leg

Pathology

Muscle lymphoma is typically the non-Hodgkin type. It can manifest in two ways 2:

  • metastatic spread from primary disease (e.g. nodal, osseous)
  • primary lesion (i.e. primary muscle lymphoma), which is less common

Radiographic appearance

MRI

Muscle enlargement with focal mass or diffuse abnormal signal 1,2:

  • T1: iso or hyperintense to normal muscle
  • T2: intermediate signal intensity to fat and muscle
  • Gad (C+): diffuse (more common), thick peripheral and/or septal marginal enhancement

Differential diagnosis

Other soft tissue tumours should be considered 4:

Infection (pyomyositis) should also be considered. 

  • -<p><strong>Muscle lymphoma</strong> is a rare manifestation of <a href="/articles/lymphoma">lymphoma</a>. </p><h4>Epidemiology</h4><p>Muscle lymphoma is rare, representing &gt;2% of all lymphomas. Average age of presentation is 70 years <sup>1</sup>. </p><h5>Risk factors</h5><ul><li>
  • +<p><strong>Muscle lymphoma</strong> is a rare manifestation of <a href="/articles/lymphoma">lymphoma</a>. </p><h4>Epidemiology</h4><p>Muscle lymphoma is rare, representing &lt;2% of all lymphomas. Average age of presentation is 70 years <sup>1</sup>. </p><h5>Risk factors</h5><ul><li>

Systems changed:

  • Haematology

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