Whipple disease (musculoskeletal manifestations)

Last revised by Henry Knipe on 19 Oct 2023

The musculoskeletal manifestations of Whipple disease are among the most constant and earliest signs of the disease and can mimic rheumatic diseases including rheumatoid arthritis or spondyloarthritis 1-3. Joint symptoms may include migrating polyarthralgia, arthritis, spondylodiscitis, myalgia, bursitis, and/or tenosynovitis 3.

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