Okuda staging system

Changed by Matt A. Morgan, 16 Jun 2015

Updates to Article Attributes

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The Okuda staging system was an advance on earlier hepatocellular (HCC) staging classifications, in that it incorporated both cancer-related variables and liver function related variables to determine prognosis 1:

  • disease involving >50% of hepatic parenchyma
  • ascites
  • albumin ≤ 3≤3 mg/dL
  • bilirubin ≥ 3≥3 mg/dL

These are combined into stages:

  • stage A: 0 criteria
  • stage B: 1-2 criteria
  • stage C: 3-4 criteria

Higher stages were correlated with a poorer prognosis.

History and etymology

The staging classification was published by K Okuda et al in 1985.

See also

  • -<li>albumin ≤ 3 mg/dL</li>
  • -<li>bilirubin ≥ 3 mg/dL</li>
  • +<li>albumin ≤3 mg/dL</li>
  • +<li>bilirubin ≥3 mg/dL</li>

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