Osteoid

Last revised by Andrew Murphy on 25 Apr 2024

Citation, DOI, disclosures and article data

Citation:

Amini B, Murphy A, Osteoid. Reference article, Radiopaedia.org (Accessed on 05 May 2024) https://doi.org/10.53347/rID-1801

DOI:

https://doi.org/10.53347/rID-1801

Permalink:

https://radiopaedia.org/articles/1801

rID:

1801

Article created:

2 May 2008, Behrang Amini

Disclosures:

At the time the article was created Behrang Amini had no recorded disclosures.

Last revised:

25 Apr 2024, Andrew Murphy ◉

Disclosures:

At the time the article was last revised Andrew Murphy had no financial relationships to ineligible companies to disclose.

Revisions:

1 time, by 1 contributor - see full revision history and disclosures

Systems:

Musculoskeletal

Osteoid is a protein mixture secreted by osteoblasts that forms the organic matrix of bone. Bone is formed when osteoid mineralizes.

Osteoid is important in several disease processes:

failure of osteoid to mineralize leads to osteomalacia in adults and rickets in children.
- focal accumulations of osteoid can lead to Milkman's pseudofractures, which are suggestive of osteomalacia.
- linear accumulations of osteoid may build perpendicular to the cortical margin and appear as Looser's zones or pseudofractures.
osteoid osteoma is composed of osteoid and woven bone, both of which can be seen as interconnected trabeculae, sheets, or isolated islands.