Ovarian epithelial tumors

Changed by Matt A. Morgan, 5 Feb 2015

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Ovarian epithelial tumours account for the ~~vast bulk of~~majority of all ovarian tumours (60-70%) and their malignant forms represent ~~more than 90~~>90% of ovarian cancers ¹. They can range from being ~~highly~~ benign to highly malignant.

Pathology

The origin and pathogenesis of epithelial ovarian cancer are poorly understood ⁵. Despite extensive studies, no precursor lesions have been found ⁵.

Classification

~~There are many ways of classifying them.~~

ovarian serous tumours
- ovarian serous cystadenoma: ~60% of serous tumours
- ovarian borderline serous cystadenoma: ~15% of serous tumours
- ovarian serous cystadenocarcinoma: ~25% of serous tumours~~; most~~ (most common malignant ovarian tumour)
ovarian mucinous tumours: ~20% of all ovarian tumours
- ovarian mucinous cystadenoma: ~80% of mucinous tumours
- ovarian borderline mucinous cystadenoma: 10-15% of mucinous tumours
- ovarian mucinous cystadenocarcinoma: ~5-10% of mucinous tumours
ovarian endometrioid tumour: 8-15% of all ovarian tumours
ovarian cystadenofibroma*/ovarian adenofibroma: can be serous, mucinous, endometrioid, clear cell, or mixed
ovarian cystadenocarcinofibroma: extremely rare
clear cell ovarian carcinoma: ~5% of ovarian cancer
Brenner tumour: 2-3% of ovarian epithelial neoplasms
undifferentiated carcinoma of the ovary: ~4% of all ovarian tumours
squamous cell carcinoma of the ovary

* sometimes classified as a separate category rather than under epithelial

Markers

elevation of serum CA-125 levels

Radiographic features

These can range from being cystic, to solid, to anything in between. As a crude rule ~~the~~, the likelihood of malignancy increases with increasing solid-tissue elements and thicker septae ². While there are some common features, there are also many variations and it may be best to refer to ~~sub articles~~subarticles for specific imaging features.

-<p><strong>Ovarian epithelial tumours </strong>account for the vast bulk of all <a href="/articles/ovarian-tumours">ovarian tumours</a> (60-70%) and their malignant forms represent more than 90% of ovarian cancers <sup>1</sup>. They can range from being highly benign to highly malignant.</p><h4>Pathology</h4><p>The origin and pathogenesis of epithelial ovarian cancer are poorly understood <sup>5</sup>. Despite extensive studies, no precursor lesions have been found <sup>5</sup>.</p><h5>Classification</h5><p>There are many ways of classifying them.</p><ul>
+<p><strong>Ovarian epithelial tumours </strong>account for the majority of all <a href="/articles/ovarian-tumours">ovarian tumours</a> (60-70%) and their malignant forms represent >90% of ovarian cancers <sup>1</sup>. They can range from being benign to highly malignant.</p><h4>Pathology</h4><p>The origin and pathogenesis of epithelial ovarian cancer are poorly understood <sup>5</sup>. Despite extensive studies, no precursor lesions have been found <sup>5</sup>.</p><h5>Classification</h5><ul>
~~-<a href="/articles/ovarian-serous-cystadenocarcinoma">ovarian serous cystadenocarcinoma</a>: ~25% of serous tumours; most common malignant ovarian tumour</li>~~
+<a href="/articles/ovarian-serous-cystadenocarcinoma">ovarian serous cystadenocarcinoma</a>: ~25% of serous tumours (most common malignant ovarian tumour)</li>
-<a href="/articles/ovarian-cystadenofibroma">ovarian cystadenofibroma</a>*/<a href="/articles/ovarian-adenofibroma">ovarian adenofibroma</a>: can be serous, mucinous, endometrioid, clear cell or mixed</li>
+<a href="/articles/ovarian-cystadenofibroma">ovarian cystadenofibroma</a>* / <a href="/articles/ovarian-adenofibroma">ovarian adenofibroma</a>: can be serous, mucinous, endometrioid, clear cell, or mixed</li>
-</ul><p>* sometimes classified as a separate category rather than under epithelial </p><h5>Markers</h5><ul><li><a href="/articles/ca-125-elevation-2">elevation of serum CA-125 levels</a></li></ul><h4>Radiographic features</h4><p>These can range from being cystic to solid to anything in between. As a crude rule the likelihood of malignancy increases with increasing solid-tissue elements and thicker septae <sup>2</sup>. While there are some common features, there are also many variations and it may be best to refer to sub articles for specific imaging features. </p>
+</ul><p>* sometimes classified as a separate category rather than under epithelial </p><h5>Markers</h5><ul><li><a href="/articles/ca-125-elevation-2">elevation of serum CA-125 levels</a></li></ul><h4>Radiographic features</h4><p>These can range from being cystic, to solid, to anything in between. As a crude rule, the likelihood of malignancy increases with increasing solid-tissue elements and thicker septae <sup>2</sup>. While there are some common features, there are also many variations and it may be best to refer to subarticles for specific imaging features. </p>

Tags changed:

gynaecology
ultrasound
pelvic mri
ovary
ovarian neoplasm

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