Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Gaillard F, Parathyroid lipoadenoma. Reference article, Radiopaedia.org (Accessed on 05 May 2024) https://doi.org/10.53347/rID-170339
Disclosures:
At the time the article was last revised Frank Gaillard had the following disclosures:
- Biogen Australia Pty Ltd, Investigator-Initiated Research Grant for CAD software in multiple sclerosis: finished Oct 2021 (past)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Frank Gaillard's current disclosures
Parathyroid lipoadenomas are extremely rare tumors that are often considered a variant of a parathyroid adenoma.
Epidemiology
There may be slight female predilection based on limited studies 2.
Clinical presentation
Patients may present with primary hyperparathyroidism.
Pathology
Histologically, almost all parathyroid lipoadenomas consist of > 50% mature adipose tissue.
Radiographic features
Ultrasound
Parathyroid lipoadenomas may be seen as juxtathyroid lesions. They may appear more echogenic/hyperechoic due to their fat content 4.
History and etymology
It is believed that parathyroid lipoadenomas were first described by Ober and Kaiser in 1958 7.
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1. Juhlin C, Falhammar H, Zedenius J, Nilsson I, Höög A. Lipoadenoma of the Parathyroid Gland: Characterization of an Institutional Series Spanning 28 Years. Endocr Pathol. 2020;31(2):156-65. doi:10.1007/s12022-020-09616-3 - Pubmed
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2. Chow L, Erickson L, Abu-Lebdeh H, Wermers R. Parathyroid Lipoadenomas: A Rare Cause of Primary Hyperparathyroidism. Endocr Pract. 2006;12(2):131-6. doi:10.4158/EP.12.2.131 - Pubmed
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3. Özden S, Güreşci S, Saylam B, Dağlar G. A Rare Cause of Primary Hyperparathyroidism: Parathyroid Lipoadenoma. Auris Nasus Larynx. 2018;45(6):1245-8. doi:10.1016/j.anl.2018.05.001 - Pubmed
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4. Cammarata F, Yakushkina A, Pennacchi L et al. Atypical Primary Hyperparathyroidism Due to Parathyroid Lipoadenoma: A Case Report. Journal of Surgical Case Reports. 2021;2021(7):rjab308. doi:10.1093/jscr/rjab308 - Pubmed
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5. Bleiweiss I, Harpaz N, Strauchen J, Wagner R, Biller H. Functioning Lipoadenoma of the Parathyroid: Case Report and Literature Review. Mt Sinai J Med. 1989;56(2):114-7. - Pubmed
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6. Aggarwal A, Wadhwa R, Aggarwal V. Parathyroid Lipoadenoma: A Rare Entity. Indian J Endocrinol Metab. 2018;22(1):174-6. doi:10.4103/ijem.IJEM_273_17 - Pubmed
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7. Turner W, Baergen R, Pellitteri P, Orloff L. Parathyroid Lipoadenoma: Case Report and Review of the Literature. Otolaryngol--Head Neck Surg. 1996;114(2):313-6. doi:10.1016/s0194-59989670193-6 - Pubmed
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