Periosteal chondrosarcoma
Updates to Article Attributes
Juxta-cortical chondrosarcomas (also, also known as periosteal chondrosarcomas), are indistinguishable histologically from conventional medullary chondrosarcomas, and are therefore graded into low, intermediate or high grade-grade tumours (see chondrosarcoma grading).
Epidemiology
Typically it occurs in adults in in their 3rdand 4th decades and is slightly slightly more frequent in males, .
Pathology
Unlike conventional chondrosarcomas, they arise from the surface of the bone, lifting the periosteum over themselves as a fibrous pseudocapsule. The underlying cortex is usually thickened or may be eroded, however, extension into the medullary cavity is not usual. Where the periosteum is lifted a Codman triangle may be seen. In addition to the usual chondroid matrix, metaplastic ossification is also common.
Location
They typically arise from long bones, with a predilection for the posterior aspect of the distal femur.
Differential diagnosis
-
periosteal osteosarcoma
- affects younger patients (typically 10-25 years of age)
- periosteal reaction perpendicular to the cortex
- diaphyseal rather than metaphyseal
-
parosteal osteosarcoma
- stalk of bony
attachementattachment - otherwise similar appearance, location and demographics
- stalk of bony
- juxtacortical chondroma
- parosteal lipoma
-<p><strong>Juxta-cortical chondrosarcomas</strong> (also known as <strong>periosteal chondrosarcomas</strong>) are indistinguishable histologically from <a href="/articles/conventional-intramedullary-chondrosarcoma">conventional medullary chondrosarcomas</a>, and are therefore graded into low, intermediate or high grade tumours (see <a href="/articles/chondrosarcoma-grading">chondrosarcoma grading</a>).</p><h4>Epidemiology</h4><p>Typically it occurs in adults in their 3<sup>rd </sup>and 4<sup>th</sup> decades and is slightly more frequent in males, .</p><h4>Pathology</h4><p>Unlike conventional chondrosarcomas, they arise from the surface of the bone, lifting the periosteum over themselves as a fibrous pseudocapsule. The underlying cortex is usually thickened or may be eroded, however extension into the medullary cavity is not usual. Where the periosteum is lifted a <a href="/articles/codman_triangle_periosteal_reaction">Codman triangle</a> may be seen. In addition to the usual chondroid matrix, metaplastic ossification is also common.</p><h5>Location</h5><p>They typically arise from long bones, with a predilection for the posterior aspect of the distal <a href="/articles/femur">femur</a>.</p><h4>Differential diagnosis</h4><ul>- +<p><strong>Juxta-cortical chondrosarcomas</strong>, also known as <strong>periosteal chondrosarcomas</strong>, are indistinguishable histologically from <a href="/articles/conventional-intramedullary-chondrosarcoma">conventional medullary chondrosarcomas</a> and are therefore graded into low, intermediate or high-grade tumours (see <a href="/articles/chondrosarcoma-grading">chondrosarcoma grading</a>).</p><h4>Epidemiology</h4><p>Typically it occurs in adults in their 3<sup>rd </sup>and 4<sup>th</sup> decades and is slightly more frequent in males.</p><h4>Pathology</h4><p>Unlike conventional chondrosarcomas, they arise from the surface of the bone, lifting the periosteum over themselves as a fibrous pseudocapsule. The underlying cortex is usually thickened or may be eroded, however, extension into the medullary cavity is not usual. Where the periosteum is lifted a <a href="/articles/codman-triangle-periosteal-reaction">Codman triangle</a> may be seen. In addition to the usual chondroid matrix, metaplastic ossification is also common.</p><h5>Location</h5><p>They typically arise from long bones, with a predilection for the posterior aspect of the distal <a href="/articles/femur">femur</a>.</p><h4>Differential diagnosis</h4><ul>
-<li>periosteal reaction perpendicular to cortex</li>- +<li>periosteal reaction perpendicular to the cortex</li>
-<a href="/articles/parosteal_osteosarcoma">parosteal osteosarcoma</a><ul>-<li>stalk of bony attachement</li>- +<a href="/articles/parosteal-osteosarcoma-1">parosteal osteosarcoma</a><ul>
- +<li>stalk of bony attachment</li>
-<li><a href="/articles/parosteal-lipoma">parosteal lipoma </a></li>- +<li><a href="/articles/parosteal-lipoma">parosteal lipoma </a></li>
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