Posterior atrophy score of parietal atrophy

Changed by Henry Knipe, 16 Sep 2015

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The posterior atrophy score, also known as the  a.k.a. Koedam score, has been developed to enable visual assessment of parietal atrophy on MRI, and is useful in the assessment of patients with possible dementia, especially atypical or early onset Alzheimer's disease (see: neurodegenerative MRI brain (an: an approach)) 1-2,2

To generate this score, the brain must be viewed in three planes, and multiple structurestructures assessed:

  1. sagittal plane
  2. coronal plane​​
  3. axial plane

The worse features are used to generate a grade of 0 to 3 1

  • grade 0: closed sulci, no gyral atrophy
  • grade 1: mild sulcal widening, mild gyral atrophy
  • grade 2: substantial sulcal widening, substantial gyral atrophy
  • grade 3: marked sulcal widening, knife-blade gyral atrophy
  • -<p>The <strong>posterior atrophy score</strong>, also known as the <strong>Koedam score</strong>, has been developed to enable visual assessment of parietal atrophy on MRI, and is useful in the assessment of patients with possible dementia, especially atypical or early onset <a href="/articles/alzheimer-disease-1">Alzheimer's disease</a> (see: <a href="/articles/neurodegenerative-mri-brain-an-approach">neurodegenerative MRI brain (an approach)</a>) <sup>1-2</sup>. </p><p>To generate this score, the brain must be viewed in three planes, and multiple structure assessed. </p><ol>
  • +<p>The <strong>posterior atrophy score</strong>, a.k.a. <strong>Koedam score</strong>, has been developed to enable visual assessment of parietal atrophy on MRI, and is useful in the assessment of patients with possible dementia, especially atypical or early onset <a href="/articles/alzheimer-disease-1">Alzheimer's disease</a> (see: <a href="/articles/neurodegenerative-mri-brain-an-approach">neurodegenerative MRI brain: an approach</a>) <sup>1,2</sup>. </p><p>To generate this score, the brain must be viewed in three planes, and multiple structures assessed:</p><ol>
  • -<li>posterior cingulate sulcus</li>
  • -<li>parieto-occipital sulcus</li>
  • -<li>precuneus gyri</li>
  • +<li><a title="posterior cingulate sulcus" href="/articles/posterior-cingulate-sulcus">posterior cingulate sulcus</a></li>
  • +<li><a title="parieto-occipital sulcus" href="/articles/parieto-occipital-sulcus">parieto-occipital sulcus</a></li>
  • +<li><a title="precuneus gyrus" href="/articles/precuneus-gyrus">precuneus gyrus</a></li>
  • -<li>posterior cingulate sulcus</li>
  • -<li>parietal gyri</li>
  • +<li><a title="posterior cingulate sulcus" href="/articles/posterior-cingulate-sulcus">posterior cingulate sulcus</a></li>
  • +<li><a title="parietal gyrus" href="/articles/parietal-gyrus">parietal gyrus</a></li>
  • -<li>posterior cingulate sulcus</li>
  • -<li>parietal lobes</li>
  • +<li><a title="posterior cingulate sulcus" href="/articles/posterior-cingulate-sulcus">posterior cingulate sulcus</a></li>
  • +<li><a title="Parietal lobes" href="/articles/parietal-lobe">parietal lobes</a></li>
  • -</ul><p> </p>
  • +</ul>

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